Quantitative Pulmonary Imaging Registry & Biorepository

NCT05530408 | Recruiting

• 1 other identifier: STUDY00148295
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this project is to establish a registry and biorepository of images and biological samples from subjects undergoing novel pulmonary imaging methods to be used for future research aimed toward identifying clinical applications of imaging methods and toward understanding the physiological significance of imaging biomarkers. This registry and biorepository will accelerate the development of these imaging techniques and may lead toward future clinical adoption of quantitative pulmonary imaging.

Conditions

Pulmonary Disease

Keywords

Xenon; Xe-129; CT

Outcome Measures

Primary Outcomes (4)

• Collect Clinical Data

  Collect relevant medical history (including demographic information, diagnoses, medical tests, smoking history), for patients participating in pulmonary imaging research.

  From Enrollment to 3 Months

• Establish a Biorepository

  Establish a collection of biospecimens from imaging subjects to foster an improved understanding of the physiological significance of imaging biomarkers.

  From Enrollment to 3 Months

• Biospecimen Collection

  Correlate imaging biomarkers with biospecimens and physiological/vital signs data.

  From Enrollment to 6 Months

• Collaborate

  Provide images and biospecimens to researchers working to develop analysis methods for pulmonary CT and MRI. Separate IRB approval, alongside appropriate data and/or materials transfer agreements will be needed for these studies.

  From Enrollment to 12 Months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participating in an Imaging Study at KUMC

You may qualify if:

• The participant is enrolling/has enrolled in a research study at the University of Kansas Medical Center that involves Pulmonary MRI and/or Pulmonary CT.

You may not qualify if:

• The participant declines to participate.

Sponsors & Collaborators

• University of Kansas Medical Center: lead

Study Sites (1)

University of Kansas Medical Center

Kansas City, Kansas, 66160, United States

RECRUITING

Related Links

• KUMC Research - Quantitative Pulmonary Imaging Core

MeSH Terms

Conditions

Lung Diseases

Condition Hierarchy (Ancestors)

Respiratory Tract Diseases

Study Officials

• Peter J Niedbalski, PhD

  Research Assistant Professor

  PRINCIPAL INVESTIGATOR

• Luigi R Boccardi, MPH

  Director of Pulmonary, Critical Care, & Sleep Research

  STUDY DIRECTOR

Central Study Contacts

Cristal Monge

CONTACT

9135882473; chernandez@kumc.edu

Adam M Ruff, BS

CONTACT

9135743932; aruff@kumc.edu

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant Professor

Study Record Dates

• First Submitted: September 2, 2022
• First Posted: September 7, 2022
• Study Start: May 24, 2022
• Primary Completion (Estimated): December 31, 2027
• Study Completion (Estimated): May 31, 2028
• Last Updated: May 6, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, ICF, CSR
• Access Criteria: Contact Peter J. Niedbalski, PhD to discuss accessing IPD.

Locations

US (1)