Imaging of Lungs With a New Type of Magnetic Resonance Imaging (MRI) Called UTE (Ultrashort Echo Time)

NCT02862418 | Completed

• 1 other identifier: CIN001-Lung UTE MRI
• Study Type: observational
• Target: 6
• Locations: 1 country
• Sites: 1

Brief Summary

This research study has 2 purposes:

1. 1.To learn about new ways to use Magnetic Resonance Imaging (MRI) to take clearer pictures of the lungs. A type of MRI called Ultra Short Echo Time (UTE) will be used as well as traditional MRI.
2. 2.To collect images and health information about lungs that have different kinds of lung diseases to compare to healthy lungs. This collection will help researchers and clinicians to better understand lung variations in health and disease.

Conditions

Pulmonary Disease

Keywords

MRI; UTE MRI; Pulmonary

Outcome Measures

Primary Outcomes (1)

• Comparison Anatomic MRI to UTE MRI

  UTE MR imaging sequences will be evaluated by a radiologist for image quality and, if applicable, will be compared to anatomic scans acquired with traditional MRI settings

  Day 1 after MRI

Study Arms (2)

Pulmonary disease

UTE MRI

Other: UTE MRI

Control

UTE MRI

Other: UTE MRI

Interventions

UTE MRI OTHER

One MRI with UTE settings will be acquired.

Control; Pulmonary disease

Eligibility Criteria

• Age: 5 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Children and adults age 5 and older with and without diagnosed pulmonary disease.

You may qualify if:

• Signed informed consent or Parental Permission
• Age ≥ 5 years
• Willing and able to comply with MRI instructions

You may not qualify if:

• History of any comorbidity reviewed at the Screening Visit that, in the opinion of the investigator, might confound the results of the study or pose an additional risk to the subject.
• Pregnancy

Sponsors & Collaborators

• Children's Hospital Medical Center, Cincinnati: lead

Study Sites (1)

Penny New

Cincinnati, Ohio, 45229, United States

Location

MeSH Terms

Conditions

Lung Diseases

Condition Hierarchy (Ancestors)

Respiratory Tract Diseases

Study Officials

• Zackary Cleveland, PhD

  Children's Hospital Medical Center, Cincinnati

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 8, 2016
• First Posted: August 11, 2016
• Study Start: October 1, 2015
• Primary Completion: July 1, 2024
• Study Completion: July 1, 2024
• Last Updated: January 7, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will share

Locations

US (1)