Effects of Myofascial Release and Neuromuscular Training for Pes Anserine Syndrome Associated With Knee Osteoarthritis

NCT05529914 | Completed DMC

• 1 other identifier: RHassan
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 2

Brief Summary

A randomized control trial will be conducted at the outpatient department of Dow Institute of Physical Medicine and Rehabilitation. A sample size of 80 is calculated using PASS version 11 software. The subjects will be first screened and those who fulfill the inclusion criteria, will be asked to fill the consent form. After selection, the participants will be randomly allocated by the help of computer generated randomization sheet, into two groups i.e. experimental and the control group. The group A will be provided with the myofascial release along with the neuromuscular training whereas the group B will only receive the neuromuscular training. Cold pack will be applied to both the groups. The neuromuscular training consists of warm-up phase, lunges, sideways exercises, wall squats, weight transfer exercises, step up and down and the cool down phase. Total 12 sessions of 35 minutes each will be given to all the participants for about 4 weeks on alternate days. Outcome measures will be analyzed by visual analogue scale (VAS) for pain assessment, goniometry for range of motion and the Knee injury and Osteoarthritis Outcome Score (KOOS) to evaluate the functional assessment of the patients at the baseline and the post intervention.

Conditions

Knee Osteoarthritis; Pes Anserine Bursitis

Outcome Measures

Primary Outcomes (2)

• Change in pain intensity on visual analogue scale after four weeks

  The Visual Analogue Scale is a unidimensional measure of pain intensity, used to record patients' pain progression, or compare pain severity between pains with similar conditions.. It is 0 to 10 cm scale. Patients rate their pain on that scale. Higher the score in centimeter, severe will be the pain experienced.

  Baseline and 4 weeks

• Change in range of motion assessed with universal goniometer after four weeks

  The Goniometer is an instrument for the precise measurement of range of movement angles in degree , especially one used to measure the angles before and after range of motion.. Increase in the degree of angle suggests increase in range of movement.

  Baseline and 4 weeks

Secondary Outcomes (1)

• Change in functional disability assessed with Knee injury and osteoarthritis outcome score after four weeks.

  Baseline and 4 weeks

Study Arms (2)

Myofascial release + Neuromuscular exercises + Cold pack

EXPERIMENTAL

Other: Myofascial release; Other: Neuromuscular exercises; Other: Cold pack

Neuromuscular exercises + Cold pack

ACTIVE COMPARATOR

Other: Neuromuscular exercises; Other: Cold pack

Interventions

Myofascial release OTHER

It is a type of physical therapy often used to treat myofascial pain syndrome with pressure.

Myofascial release + Neuromuscular exercises + Cold pack

Neuromuscular exercises OTHER

Exercises commonly utilized in neuromuscular training programs to improve strength, balance , speed and agility. It will comprised of Warm-up, Lunges, Sideways exercises, Wall squats, Weight transfer exercise, Step up \& down, Cool-down

Myofascial release + Neuromuscular exercises + Cold pack; Neuromuscular exercises + Cold pack

Cold pack OTHER

Application of cold pack around the patient's body, and covered with dry towel

Also known as: Cold pack therapy

Myofascial release + Neuromuscular exercises + Cold pack; Neuromuscular exercises + Cold pack

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Male and Females both with the age between 40-60 years.
• Patients with unilateral or bilateral knee osteoarthritis with pes anserine syndrome.
• Patients with knee pain more than 3.4 cm on visual analogue scale as minimum cut of value.
• Kellgren and Lawrence grade II and III on radiological findings.
• Duration of knee osteoarthritis more than 3 months (chronic).

You may not qualify if:

• Patients with any neurological disorder.
• Knee deformities such as contractures, genu valgum and genu varum.
• Septic knee arthritis.
• History of ligamentous injury or meniscal tear.
• Cancer or any other malignancy or bone tumor.
• Any history of previous lower limb arthroplasty or other knee surgery.
• Comorbid like diabetes mellitus.
• Inflammatory rheumatic disease (R.A).

Sponsors & Collaborators

• Dow University of Health Sciences: lead

Study Sites (2)

Dow Institute of Physical Medicine and Rehabilitation

Karachi, Sindh, 74200, Pakistan

Location

Sindh Institute of Physical Medicine and Rehabilitation

Karachi, Sindh, 74200, Pakistan

Location

MeSH Terms

Conditions

Osteoarthritis, Knee; Bursitis

Interventions

Myofascial Release Therapy

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Massage; Therapy, Soft Tissue; Musculoskeletal Manipulations; Complementary Therapies; Therapeutics; Physical Therapy Modalities; Rehabilitation

Study Officials

• Farhan I Khan, PhD

  Dow University of Health Sciences

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 3, 2022
• First Posted: September 7, 2022
• Study Start: September 27, 2022
• Primary Completion: March 30, 2023
• Study Completion: April 30, 2023
• Last Updated: January 9, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

PA (2)