NCT05529186

Brief Summary

The causes of mortality in kidney transplant patients and the risk factors for mortality have been widely published. However, there is a high variability according to geographical areas and time. Recent studies suggest that the classical hierarchy of causes of mortality, i.e. the predominance of cardiovascular causes of death, could be overturned by the increase in infectious and cancer-related deaths. Investigators will try to highlight this paradigm shift and the related risk factors by studying two large French transplantation databases.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
7,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 14, 2022

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

August 30, 2022

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 6, 2022

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 14, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 14, 2023

Completed
Last Updated

November 8, 2023

Status Verified

November 1, 2023

Enrollment Period

1.8 years

First QC Date

August 30, 2022

Last Update Submit

November 7, 2023

Conditions

Renal Disease

Keywords

renal diseasekidney transplant

Outcome Measures

Primary Outcomes (1)

  • Distribution of the causes of death of kidney transplant recipients presented in the form of percentage

    Six months of starting dialysis

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult subject (≥18 years old) with transplantation performed between 01/01/2008 and 31/12/2014

You may qualify if:

  • Adult subject (≥18 years old) during transplantation
  • Transplantation performed between 01/01/2008 and 31/12/2014
  • Kidney transplant subject, double transplants kidney + pancreas, or kidney + islets of Langherans
  • Subject previously transplanted other organs
  • Subject not objecting, after being informed, to the reuse of their data for the purposes of this research

You may not qualify if:

  • Subject who expressed their opposition to participating in the study
  • Subject having received a double transplant during the same operation: kidney + heart, kidney + liver, kidney + lungs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Service Néphrologie-Dialyse-Transplantation - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Kidney Diseases

Condition Hierarchy (Ancestors)

Urologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Central Study Contacts

Sophie CAILLARD, MD, PhD

CONTACT

33 3 69 55 51 20sophie.caillard@chru-strasbourg.fr

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 30, 2022

First Posted

September 6, 2022

Study Start

March 14, 2022

Primary Completion

December 14, 2023

Study Completion

December 14, 2023

Last Updated

November 8, 2023

Record last verified: 2023-11

Locations

FR(1)