The Effect of Different Muscle Training on Activities of Daily Living in COPD

NCT05501457 | Unknown

• 1 other identifier: HititUApayas
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic obstructive pulmonary disease (COPD) contributes significantly to global morbidity and mortality; It is a disease that affects an estimated 210 million people worldwide and is the third most common cause of death. COPD is identified by persistent airflow limitation and is associated with progressively worsening lung function, dyspnea, health-related quality of life (HRQOL), and impaired exercise capacity. Poor exercise capacity is a common finding of chronic obstructive pulmonary disease (COPD). Central cardiopulmonary factors, respiratory muscle dysfunction, gas exchange abnormalities, and skeletal muscle dysfunction all play a role in limiting exercise capacity The aim of this study is to investigate the effects of neuromuscular electrical stimulation applied to different muscle groups (quadriceps femoris and gastrocnemius muscles) on exercise performance and quality of life in patients with stable COPD and compare it with standard treatment.

Conditions

Quality of Life; Anxiety

Keywords

COPD; Pulmonary rehabilitation; Neuromuscular electrical stimulation

Outcome Measures

Primary Outcomes (1)

• 6 Minute Walk Test (6 MWT):

  they could walk for 6 minutes, according to heart rate, blood pressure, respiratory rate, finger oxygen saturation, the walking distance at the end of walking, and dyspnea score according to the Modified Borg Scale (MBS) at the beginning and end of walking was recorded. Change from baseline 6 Minute walking performance after 4 weeks will be examined.

  4 weeks

Secondary Outcomes (3)

• Modified Borg Scale (MBS):

  4 weeks

• St. George's Respiratory Questionnaire (SGRQ):

  4 weeks

• Beck Depression Inventory (BDI):

  4 weeks

Study Arms (3)

The gastrocnemius group

EXPERIMENTAL

The patients in the first group (n=15) were given a pulmonary rehabilitation program and additionally 20 minutes of Neuromuscular electrical stimulation (Group 1) to the gastrocnemius muscle,

Device: Muscle strengthening with neuromuscular electrical stimulation

The quadriceps femoris group

EXPERIMENTAL

The second group was given a pulmonary rehabilitation program and an additionally 20 minutes of neuromuscular electrical stimulation to the quadriceps femoris muscle (Group 2),

Device: Muscle strengthening with neuromuscular electrical stimulation

The control group

EXPERIMENTAL

The third group, which was the control group, was given only a pulmonary rehabilitation program (Group 3).

Device: Muscle strengthening with neuromuscular electrical stimulation

Interventions

Muscle strengthening with neuromuscular electrical stimulation DEVICE

The effect of peripheral muscle strengthening training in addition to pulmonary rehabilitation in COPD patients on the patient's performance will be examined.

The control group; The gastrocnemius group; The quadriceps femoris group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being between 18-75 years old,
• Diagnosed as group B stable COPD according to GOLD criteria by a pulmonologist,
• PaO2 \>55 mm Hg, PaCO2 \<45 mmHg in room air.

You may not qualify if:

• Exacerbation,
• Cor pulmonale or respiratory muscle fatigue (abdominal paradoxical breathing),
• Cardiac instability (with acute MI, congestive heart failure, or uncontrollable arrhythmia),
• Musculoskeletal disorder (conditions affecting exercise ability),
• Difficulty communicating.

Sponsors & Collaborators

• Hitit University: lead

Study Sites (1)

Hititi University Sungurlu Vocational School

Çorum, 19000, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Anxiety Disorders; Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Mental Disorders; Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Ahmet Payas, Dr

  HİTİT UNIVERSITY CORUM EROL OLCOK EDUCATION AND RESEARCH HOSPITAL

  STUDY DIRECTOR

Central Study Contacts

Ahmet Payas, Dr

CONTACT

05343483399; ahmetpayas@hitit.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director

Study Record Dates

• First Submitted: August 9, 2022
• First Posted: August 15, 2022
• Study Start: July 15, 2022
• Primary Completion: October 1, 2022
• Study Completion: November 1, 2022
• Last Updated: August 15, 2022

Record last verified: 2022-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)