NCT05497427

Brief Summary

The purpose of this study is to collect normative test values and demographic information for normative and referential data for a rapid, portable, computerized neurocognitive testing device from healthy adults 50 and older.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2022

Typical duration for all trials

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 5, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 11, 2022

Completed
2 months until next milestone

Study Start

First participant enrolled

October 10, 2022

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 17, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 17, 2025

Completed
Last Updated

January 2, 2026

Status Verified

December 1, 2025

Enrollment Period

3 years

First QC Date

August 5, 2022

Last Update Submit

December 29, 2025

Conditions

Keywords

Healthy VolunteersDementiaAlzheimer's DiseaseMild Cognitive ImpairmentOlder Adults

Outcome Measures

Primary Outcomes (1)

  • Mean, standard deviation, and percentiles of values of BrainCheck Assessments

    BrainCheck Assessment values will be calculated by descriptive statistics. Mean, standard deviation, and percentiles (1, 5, 10, 25, 50, 75, 90, 95, 99) of the scores will be calculated for each individual assessment.

    5 months

Secondary Outcomes (1)

  • Test-retest reliability of BrainCheck Assessment values between two different time points

    5 months

Study Arms (3)

Normative

BrainCheck assessment values from participants that have indications of healthy cognition at the time of testing ( a SLUMS result considered 'normal', more than 4 hours of sleep the night before, not having consumed alcohol or drugs within the last 6 hours, or not have participated in high capacity and strenuous physical activity within the last hour.)

Device: BrainCheck Assessment

Test-Retest

Comparing BrainCheck assessment values between an initial visit test and a follow-up visit test 7-14 days later within subjects.

Device: BrainCheck Assessment

Per Protocol

BrainCheck assessment values from participants that completed all procedures with no protocol deviations

Device: BrainCheck Assessment

Interventions

A computerized neurocognitive test administered via an electronic device, such as a phone, tablet or computer, that contains several assessments that will aid in establishing an individuals cognitive performance

NormativePer ProtocolTest-Retest

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population will consist of healthy volunteers 50 years of age or older.

You may qualify if:

  • Aged 50 or older
  • Willing and able to comply with study requirements and activities

You may not qualify if:

  • TBI within the last 6 months
  • Neurosurgery within the last month
  • Experienced a stroke
  • Self reported neurological condition (including mild neuropsychological impairment, dementia, Parkinson's disease, amyotrophic lateral sclerosis, Multiple sclerosis, or long-covid)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

BrainCheck

Palo Alto, California, 94301, United States

Location

Maplewood Senior Living

Multiple Locations, Connecticut, 06880, United States

Location

BrainCheck

Austin, Texas, 78702, United States

Location

BrainCheck

Houston, Texas, 77005, United States

Location

BrainCheck

Seattle, Washington, 98105, United States

Location

MeSH Terms

Conditions

Cognitive DysfunctionDementiaAlzheimer Disease

Condition Hierarchy (Ancestors)

Cognition DisordersNeurocognitive DisordersMental DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative Diseases

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 5, 2022

First Posted

August 11, 2022

Study Start

October 10, 2022

Primary Completion

October 17, 2025

Study Completion

October 17, 2025

Last Updated

January 2, 2026

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations