NCT05490979

Brief Summary

Many people are experiencing low well-being and loneliness, particularly due to the COVID-19 pandemic. As the world is opening back up, it is crucial to determine methods to help people grow closer again and boost subjective well-being. One promising method is contemplative dyad meditation, which has hardly been studied. This is a method in which two people have a structured dialogue with each other while contemplating a prompt, as they alternate between listening and speaking. It is related to but different from other methods that have previously been shown to increase connection, such as the "fast friends" exercise. In "fast friends", two people answer a series of increasingly personal questions in a dialogue. Here, 180 participants between 18-35 years will be randomly allocated to three conditions (stratified by gender): (a) contemplative dyad meditation training, (b) "fast friends", or (c) no-intervention. Participants in the dyad meditation group will receive professional meditation training followed by 2 weeks of regular meditation practice. Participants in the "fast friends" group will meet regularly during 2 weeks to practice "fast friends" exercises. The impact of the interventions on well-being, loneliness, mindfulness, and related measures will be investigated. After the interventions have finished, participants' physiology (heart rate) and brain waves (using electroencephalography \[EEG\]) during the respective exercises will also be measured to explore potential biological mechanisms. Of particular interest are heart rate variability (HRV, often linked with higher well-being), frontal alpha asymmetry in the EEG (linked with positive affect and approach), and biological synchrony in these variables between the two interacting individuals. Both dyad meditations and "fast friends" exercises are predicted to improve closeness, thriving, loneliness, affect, depression, anxiety, and social interaction anxiety compared to no-intervention. Moreover, dyad meditation is predicted to have stronger effects than "fast friends" in terms of increasing mindfulness, self-compassion, and empathy. Dyad meditation and fast friends will show differential physiological signatures (e.g., lower heart rate and higher averaged alpha power for meditation). This study may reveal effective methods to improve well-being and connection and provide insights into their biological mechanisms.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 4, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 8, 2022

Completed
29 days until next milestone

Study Start

First participant enrolled

September 6, 2022

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 22, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 3, 2023

Completed
Last Updated

October 5, 2023

Status Verified

October 1, 2023

Enrollment Period

10 months

First QC Date

August 4, 2022

Last Update Submit

October 3, 2023

Conditions

Outcome Measures

Primary Outcomes (4)

  • Brief Inventory of Thriving

    The Brief Inventory of Thriving (Su, Tay, \& Diener, 2014) is a questionnaire consisting of 10 items, measuring psychological well-being. Scores range from 1 to 5 with a higher score indicating more thriving (i.e., higher well-being).

    3 weeks

  • Loneliness Scores on the Comprehensive Inventory of Thriving

    The Loneliness sub-scale from the Comprehensive Inventory of Thriving (Su, Tay, \& Diener, 2014) consists of 3 items. Scores range from 1 to 5 with a higher score indicating higher loneliness.

    3 weeks

  • Mindfulness Score on the Five Facet Mindfulness Questionnaire

    The Five Facet Mindfulness Questionnaire (Baer et al., 2006) consists of 39 items. Scores for mindfulness range between 1 and 5 with a higher score indicating more mindfulness.

    3 weeks

  • Inclusion of Other in the Self Scale

    The Inclusion of Other in the Self Scale (Aron, Aron, \& Smollan, 1992) consists of 7 response options measuring closeness to another person (here: the meditation or exercise partner). The response options each show two circles labeled as" "Self" and "Other", which vary in terms of overlap, from barely touching (1, i.e., not close at all) to almost completely overlapping (7, i.e., extremely close).

    Directly after each individual meditation or "fast friends" exercise

Secondary Outcomes (10)

  • Positive Affect Scores on the Negative And Positive Affect Scale

    3 weeks

  • Negative Affect Scores on the Negative And Positive Affect Scale

    3 weeks

  • Depression Scores on the Patient Health Questionnaire-9

    3 weeks

  • Generalized Anxiety Disorder-7 questionnaire

    3 weeks

  • Social Interaction Anxiety Scale-6

    3 weeks

  • +5 more secondary outcomes

Other Outcomes (4)

  • Heart rate

    3 weeks

  • Heart rate variability

    3 weeks

  • Respiration

    3 weeks

  • +1 more other outcomes

Study Arms (3)

Contemplative dyad meditation

EXPERIMENTAL
Behavioral: Contemplative dyad meditation

Fast friends

ACTIVE COMPARATOR
Behavioral: Fast friends

No intervention

NO INTERVENTION

Interventions

Participants take part in a 3-hour group meditation training led by a professional meditation teacher. They receive detailed instructions and also practice contemplative dyad meditation for at least 30 minutes with another participant. During the 2 weeks following the training, participants meet in supervised group settings to practice the meditation method with alternating partners for up to 6 times.

Contemplative dyad meditation
Fast friendsBEHAVIORAL

During 2 weeks, participants meet in supervised group settings to practice the 'fast friends' exercise with alternating partners for up to 6 times.

Fast friends

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Current student, staff, or employee at the University of Pennsylvania (for safety reasons)

You may not qualify if:

  • none

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

Study Officials

  • Michael L Platt, PhD

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Participants only receive information about the condition they have been assigned to and are not explicitly informed about the other conditions or the overall purpose of the study. All participants will be debriefed when the study has ended.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
James S. Riepe University Professor

Study Record Dates

First Submitted

August 4, 2022

First Posted

August 8, 2022

Study Start

September 6, 2022

Primary Completion

June 22, 2023

Study Completion

October 3, 2023

Last Updated

October 5, 2023

Record last verified: 2023-10

Locations