NCT05490069

Brief Summary

The proposed pilot trial aims to evaluate the feasibility of iCBT based EMI, which is a real-time, real-world, personalised and cost-effective approach, for stroke survivors' psychological well-being.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable stroke

Timeline
Completed

Started Oct 2021

Geographic Reach
1 country

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 4, 2021

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

August 3, 2022

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 5, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 23, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 23, 2022

Completed
Last Updated

May 1, 2023

Status Verified

April 1, 2023

Enrollment Period

1.2 years

First QC Date

August 3, 2022

Last Update Submit

April 27, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Depressive symptoms (Patient Health Questionnaire-9 [PHQ-9])

    A 9-item scale with score ranging from 0 to 27, higher scores indicate higher severity of depressive symptom

    24-week

Secondary Outcomes (4)

  • Anxiety symptoms (Generalized Anxiety Disorder-7 [GAD-7])

    24-week

  • Stress level (Perceived Stress Scale [PSS-4])

    24-week

  • Spiritual well-being (Sub-scale of Spirituality Scale for Chinese Elders [SSCE])

    24-week

  • Loneliness (UCLA Loneliness Scale [ULS-8])

    24-week

Study Arms (2)

Intervention group

EXPERIMENTAL

Receive iCBT based EMI with message content, delivery frequency and timing personalised to participants' preferences.

Other: iCBT-based EMI

Control group

NO INTERVENTION

Receive general mental health information through instant message.

Interventions

Consists of brief iCBT for psychological support (mandatory), stroke care education (optional), and real-time chat-based support messages, delivered according to participants' preferences.

Intervention group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of stroke (ICD-10 codes: I60-I69)
  • Aged ≥18
  • Able to read and communicate in Chinese (Cantonese or Putonghua)
  • Able to use text messaging function on mobile phones
  • MoCA 5-minute Protocol (cognitive screen) ≥14 (Equivalence to MMSE ≥ 21)
  • Discharged home from hospital within preceding 6 months
  • PHQ-9 (depressive symptom) score range from 5 to 19 (cf. mild: 5-9, moderate: 10-14, moderately severe: 15-19 and severe: 20-27)

You may not qualify if:

  • Currently receiving active stroke care in acute or post-acute inpatient settings
  • Has diagnosis of psychiatric disease or is currently taking psychotropic drug
  • PHQ-9 ≥ 20 (i.e., severe depressive symptom)
  • Currently participating in any type of psychological intervention (e.g., CBT)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

Hong Kong PHAB Association

Hong Kong, Hong Kong

Location

Hong Kong Stroke Association

Hong Kong, Hong Kong

Location

NT West Community Rehabilitation Day Centre

Hong Kong, Hong Kong

Location

Queen Mary Hospital

Hong Kong, Hong Kong

Location

The Hong Kong Society for Rehabilitation

Hong Kong, Hong Kong

Location

Tung Wah Hospital

Hong Kong, Hong Kong

Location

United Christian Hospital

Hong Kong, Hong Kong

Location

MeSH Terms

Conditions

StrokeDepressionCell Phone Use

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesBehavioral SymptomsBehaviorCommunicationSocial Behavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 3, 2022

First Posted

August 5, 2022

Study Start

October 4, 2021

Primary Completion

December 23, 2022

Study Completion

December 23, 2022

Last Updated

May 1, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will not share

Locations