NCT04936828

Brief Summary

The proposed trial aims to evaluate the effectiveness of internet-delivered cognitive behavioural therapy (iCBT) based ecological momentary intervention (EMI) for psychological well-being in stroke family caregivers.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
256

participants targeted

Target at P75+ for not_applicable stroke

Timeline
Completed

Started Sep 2021

Geographic Reach
1 country

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 15, 2021

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 23, 2021

Completed
3 months until next milestone

Study Start

First participant enrolled

September 17, 2021

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2023

Completed
Last Updated

July 11, 2024

Status Verified

July 1, 2024

Enrollment Period

1.8 years

First QC Date

June 15, 2021

Last Update Submit

July 10, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Depressive symptoms (Patient Health Questionnaire-9 [PHQ-9])

    A 9-item scale with score ranging from 0 to 27, higher scores indicate higher severity of depressive symptom

    24-week

Secondary Outcomes (6)

  • Anxiety symptoms (Generalized Anxiety Disorder-7 [GAD-7])

    24-week

  • Stress level (Perceived Stress Scale [PSS-4])

    24-week

  • Caregiver's burden (Zarit Burden Interview [ZBI-4])

    24-week

  • Caring experience (Positive Aspects of Caregiving [PAC])

    24-week

  • Spiritual well-being (Sub-scale of Spirituality Scale for Chinese Elders [SSCE])

    24-week

  • +1 more secondary outcomes

Study Arms (2)

Intervention group

EXPERIMENTAL

Receive iCBT based EMI with message content, delivery frequency and timing personalised to participants' preferences.

Other: iCBT-based EMI

Control group

NO INTERVENTION

Receive general mental health information through instant message.

Interventions

Consists of brief iCBT for psychological support (mandatory), stroke care education (optional), and nurse-led real-time chat-based support messages, delivered according to participants' preferences.

Intervention group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Primary family caregiver of stroke patient (modified Barthel Index \[mBI\] \<15; usually represent moderate disability)
  • Able to read and communicate in Chinese
  • Aged ≥18
  • Able to use mobile phone text messaging function
  • PHQ-9 ranged from 5 to 19

You may not qualify if:

  • Professional medical personnel and professional carer
  • Has provided care for \<1 month prior to recruitment
  • Has diagnosis of psychiatric disease or is currently taking psychotropic drug
  • PHQ-9 ≥ 20 (i.e., severe depressive symptom)
  • Currently participating in any type of psychological intervention (e.g., CBT)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

Hong Kong PHAB Association

Hong Kong, Hong Kong

Location

Hong Kong Stroke Association

Hong Kong, Hong Kong

Location

NT West Community Rehabilitation Day Centre

Hong Kong, Hong Kong

Location

Queen Mary Hospital

Hong Kong, Hong Kong

Location

The Hong Kong Society for Rehabilitation

Hong Kong, Hong Kong

Location

Tung Wah Hospital

Hong Kong, Hong Kong

Location

United Christian Hospital

Hong Kong, Hong Kong

Location

MeSH Terms

Conditions

StrokeCaregiver BurdenDepressionCell Phone Use

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesStress, PsychologicalBehavioral SymptomsBehaviorCommunicationSocial Behavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 15, 2021

First Posted

June 23, 2021

Study Start

September 17, 2021

Primary Completion

June 30, 2023

Study Completion

June 30, 2023

Last Updated

July 11, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share

Locations