Ultrasonographic Measurements of the Achilles Tendon and Talar Condylar Cartilage Thickness in Paraplegia Patients.

NCT05483764 | Active Not Recruiting

• 1 other identifier: AIBU-FTR-SK-03
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Investigators aim to measure the ankle talar cartilage and achilles tendon thicknesses ultrasonographically in paraplegic patients and compare them with the normal population.

Conditions

Paraplegia

Outcome Measures

Primary Outcomes (2)

• Ankle talar cartilage thicknesses

  Patients will lie on the examination table supine with their knees flexed to 90 degrees and ankles in a flat-footed position. The probe was placed mid-longitudinally over the ankle joint to assess the cartilage of the talar dome. The articular cartilage will be displayed as an anechoic line between bony cortex and adipose tissue. Cartilage thickness will be measured by drawing a straight line from the bone-cartilage interface to the cartilage-fatty tissue interface at the midpoint of the talar dome. The thickness of the hyaline cartilage will be measured in centimeters (cm).

  1 day

• Achilles tendon thicknesses

  Ultrasound (US) evaluation will be performed with patients in the prone position on examination table with their feet in 90 degrees of flexion. Achilles tendon of the each patient and healthy volunteer will be scanned. Antero-posterior achilles thickness will be measured on the same mid-longitudinally scan at two different levels: at the insertion of the achilles tendon deeper edge into the calcaneal bone and 3 cm more proximal. The thickness of the achilles tendon will be measured in centimeters (cm).

  1 day

Study Arms (2)

Paraplegia

Device: Ultrasonographic evaluations

Control

Device: Ultrasonographic evaluations

Interventions

Ultrasonographic evaluations DEVICE

Ultrasonographic evaluations of the talar cartilage will be performed with an 8 MHz linear probe (B-K Medical Ultrasound Scanner Class I Type B) by the same physiatrist according to the European Musculoskeletal Ultrasound Study Group (EURO-MUSCULUS). Ultrasonographic evaluations of the Achilles tendon will be performed by the same physiatrist with an 8 MHz linear probe (B-K Medical Ultrasound Scanner Class I Type B) according to the European Musculoskeletal Ultrasound Study Group (EURO-MUSCULUS).

Control; Paraplegia

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The control group will be composed of healthy individuals who are compatible with the patient group in terms of age, gender and weight.

You may qualify if:

• Patients who are paraplegic after traumatic spinal cord injury (ASIA A-D)
• Healthy volunteers older than 18 years for control patients.

You may not qualify if:

• Patients who had a previous trauma-related operation on the ankle.
• Patients who had fixed contracture or severe spasticity on the ankle.
• Patients who had lower-limb length difference of more than 2 cm.

Sponsors & Collaborators

• Abant Izzet Baysal University: lead

Study Sites (1)

Abant Izzet Baysal University

Bolu, 14100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Paraplegia

Condition Hierarchy (Ancestors)

Paralysis; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: July 28, 2022
• First Posted: August 2, 2022
• Study Start: August 1, 2022
• Primary Completion: March 30, 2025
• Study Completion: March 30, 2025
• Last Updated: February 26, 2025

Record last verified: 2025-02

Locations

TU (1)