A Rehabilitation Program to Increase Balance and Mobility in Ataxia of Charlevoix-Saguenay
A Better Trunk and Lower Limb Control for a Better Mobility: Assessment of a Re-entrainment Program in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay
1 other identifier
interventional
10
1 country
1
Brief Summary
This exploratory study used a pre-post test design. The supervised rehabilitation program was performed three times a week for 8 weeks (two sessions at a rehabilitation gym and one pool session). Outcome measures included Ottawa sitting scale, 30-Second Chair Stand test, Berg Balance Scale, 10-Meter Walk Test, 6-minute Walk Test, modified Activities-specific Balance Confidence Scale and SARA scale. 10 participants will complete the training program. They will be evaluated at baseline, at week 4 (miway) and after the program.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started May 2019
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 13, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 12, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
July 12, 2019
CompletedFirst Submitted
Initial submission to the registry
July 26, 2022
CompletedFirst Posted
Study publicly available on registry
July 29, 2022
CompletedMay 24, 2023
May 1, 2023
2 months
July 26, 2022
May 22, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Change in the Scale for the assessement and rating of ataxia (SARA)
Measured with the Scale for the assessement and rating of ataxia (SARA), score range 0-40, higher score indicates higer ataxia severity
Baseline, week 4, week 8
Secondary Outcomes (6)
Change in walking speed
Baseline, week 4, week 8
Change in the number of sit-to-stand performed in 30 seconds
Baseline, week 4, week 8
Change in the balance confidence
Baseline, week 4, week 8
Change in balance
Baseline, week 4, week 8
Change in sitting balance
Baseline, week 4, week 8
- +1 more secondary outcomes
Study Arms (1)
Training program
EXPERIMENTAL8-week rehabilitation program aimed at increasing trunk and lower limb motor control on balance and walking abilities, and accomplishment of activities of daily living.
Interventions
8-week rehabilitation program aimed at increasing trunk and lower limb motor control on balance and walking abilities, and accomplishment of activities of daily living.
Eligibility Criteria
You may qualify if:
- Genetically confirmed ARSACS diagnosis; walker (indoor walking abilities with or without walking aids); ability to walk 10 meters; ability to provide informed consent
You may not qualify if:
- Having other medical diagnosis causing physical limitations
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Élise Duchesnelead
- Muscular Dystrophy Canadacollaborator
Study Sites (1)
Groupe de recherche interdisciplinaire sur les maladies neuromusculaires
Saguenay, Quebec, G7X 7X2, Canada
MeSH Terms
Conditions
Study Officials
- PRINCIPAL INVESTIGATOR
Cynthia Gagnon, PhD
Sherbrooke University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
July 26, 2022
First Posted
July 29, 2022
Study Start
May 13, 2019
Primary Completion
July 12, 2019
Study Completion
July 12, 2019
Last Updated
May 24, 2023
Record last verified: 2023-05