Oxygen Consumption in Post-stroke Patients During Various Walking Activities Compared to Healthy Controls

NCT05477238 | Completed

• 1 other identifier: 87RI22_0005 (STROXCO)
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Stroke is major public health issue. The investigators recommend post-stroke patients to practice physical activity. Nevertheless, the recommendations are not widely respected due to the intensity of exercises. Oxygen consumption is a parameter to assess the intensity of physical activity. in this sense, we want to measure the oxygen consumption during various walking tasks compared to healthy controls.

Conditions

Cerebrovascular Accident

Keywords

Stroke; Oxygen consumption; physical activity

Outcome Measures

Primary Outcomes (2)

• Oxygen consumption measurement

  Oxygen consumption by indirect calorimetry (respiratory gas exchange analyzer: Metamax) expressed in mL.min-1.kg-1

  Day 1

• Oxygen consumption measurement

  Oxygen consumption by indirect calorimetry (respiratory gas exchange analyzer: Metamax) expressed in mL.min-1.kg-1

  Day 7

Secondary Outcomes (8)

• Walking speed measurement

  Day 1

• Walking speed measurement

  Day 7

• Cardiac frequency measurement

  Day 1

• Cardiac frequency measurement

  Day 7

• Perception of effort

  Day 1

Study Arms (2)

Cerebrovascular Accident

EXPERIMENTAL

Stroke patients will perform 2 walking tests indoors and outdoors wearing a gas exchange analyzer, an accelerometer and a heart rate monitor meter

Procedure: walking tasks

healthy volunteer

OTHER

Healthy volunteers patients will perform 2 walking tests indoors and outdoors wearing a gas exchange analyzer, an accelerometer and a heart rate monitor meter

Procedure: walking tasks

Interventions

walking tasks PROCEDURE

The experiment will be divided in two sessions. In the first session, the participant/healthy volunteers will do 3 walking tasks (over ground walking/ climbing up, down stairs). In the second session, the participant will walk outside in front of the hospital (walking on a slope, walking down, walking on uneven ground). All those tasks will be done while wearing a gas exchange analyzer, accelerometer and a heart rate meter.

Cerebrovascular Accident; healthy volunteer

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Common to both groups:
• Age \>=18 years
• Able to give consent
• Not under guardianship or curatorship
• Enrolled in the French social security system
• Specific to the cerebrovascular accident Group:
• Stroke confirmed by brain imaging
• Able to walk stairs without human assistance (modified Functional Ambulation Classification \>= 6)
• Healthy Group Specific:
• \- Individuals matched to stroke individuals on age sex and BMI.

You may not qualify if:

• Cerebrovascular accident group - Severe cognitive impairment (MoCA \< 18)
• Common to both groups:
• \- Presence of contraindication to physical activity: unstable diabetes, unstable hypertension, unstable angina, intra-cardiac thrombus.

Sponsors & Collaborators

• University Hospital, Limoges: lead

Study Sites (1)

Limoges university hospital

Limoges, 87042, France

Location

MeSH Terms

Conditions

Stroke; Motor Activity

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Monocentric, cross-sectional and comparative study

Study Record Dates

• First Submitted: June 23, 2022
• First Posted: July 28, 2022
• Study Start: September 7, 2022
• Primary Completion: June 26, 2023
• Study Completion: June 26, 2023
• Last Updated: July 21, 2023

Record last verified: 2023-07

Locations

FR (1)