Identifying Drug-related Problems at ED Triage (DRP-EDiT) V1

NCT05476705 | Unknown

• 1 other identifier: IRAS 307523
• Study Type: observational
• Target: 110
• Locations: 0 countries
• Sites: N/A

Brief Summary

Up to a third of patients who visit emergency departments (EDs) do so because they have an issue with medicines prescribed by their doctor or purchased over the counter. For example, some patients might experience side effects (e.g., sickness), whereas others may feel their prescribed medicine is not working and want an alternative. While some patients who visit EDs know they have a problem with their medication, some are not aware. Furthermore, drug-related problems (DRPs) may not be identified by ED triage systems which are used to sort patients' priority for treatment. The currently used system in the UK (Manchester Triage System) mentions drugs infrequently and does not support the identification of the most common DRPs. For this project, DRPs include medication errors, adverse drug events, and adverse drug reactions. This project aims to revise the triage system to support the discovery of patients' medication problems when they are triaged by a nurse upon arrival to the ED. After identification, problems with a patient's medication should be dealt with by the healthcare professional who is most appropriate to manage that particular issue. For example, a patient who has been prescribed a new medicine but already takes 20 medicines will likely benefit from a review by a pharmacist in the ED. This project will aim to support the management of patients who might benefit from care provided by pharmacists by providing them with this care. As well as ensuring medication problems are identified at triage, and that pharmacists are involved in helping to deal with those problems, this project will also try to understand how we can investigate how pharmacists actually make a difference to the care of ED patients. A multi-step approach (Stages A-F) is proposed to answer the question "How can patient DRPs be identified, triaged and managed in the ED?" In summary, the steps include: STAGE A, a systematic review and scoping survey; STAGE B, researcher visits to ED sites to shadow ED staff; STAGE C, Interviews with healthcare professionals (including those shadowed in STAGE B) to validate findings of site visits and explore topics in more depth; STAGE D, developing additional drug-related content for the Manchester Triage System; STAGE E, involving a panel of experts in a RAND appropriateness method to rate the content developed in STAGE D; STAGE F, testing the revised triage system for a future pilot study involving interviews with staff visited in STAGE B.

Conditions

Medication Administered in Error; Medication Adverse Effects; Medication Reaction

Keywords

Drug-related problems; Emergency department; Triage; Identification; Management; Pharmacists

Outcome Measures

Primary Outcomes (1)

• Suitability of a revised Manchester Triage System (MTS)

  The suitability of a revised MTS to support identification and management of drug-related problems in the Emergency Department

  13 months (the revised MTS will be an output from the analysis of data collected months 1 - 13)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Hospital Emergency Department staff and clinicians and academics with expertise in Emergency Care and/or ED Triage

You may qualify if:

• STAGE A: ED clinicians at UK-wide NHS trusts
• STAGE B: ED staff from 8 NHS sites across the UK
• STAGE C: ED staff from 8 NHS sites across the UK
• STAGE E: Clinicians and academics with expertise in Emergency Care and/or ED Triage
• STAGE F: ED staff from 8 NHS sites across the UK

You may not qualify if:

• Those who do not consent or who are unable to consent

Sponsors & Collaborators

• Anglia Ruskin University: lead
• Pharmacy Research UK: collaborator
• University of Manchester: collaborator
• Ashford and St. Peter's Hospitals NHS Trust: collaborator

MeSH Terms

Conditions

Drug-Related Side Effects and Adverse Reactions; Emergencies

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Daniel Greenwood

  Anglia Ruskin University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Daniel Greenwood

CONTACT

01245683082; daniel.greenwood@aru.ac.uk

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 22, 2022
• First Posted: July 27, 2022
• Study Start: April 1, 2023
• Primary Completion: September 1, 2023
• Study Completion: September 1, 2023
• Last Updated: February 1, 2023

Record last verified: 2022-07