Comparison of the Effect of Cryotherapy Application and Low Level Laser Application on Post-Operative Pain in Primary Molar Teeth With Apical Periodontitis
Sponsor study identifier
interventional
75
1 country
1
Study Start
May 2, 2022
Actual (reported)Primary Completion
June 3, 2022
Actual (reported)Study Completion
June 17, 2022
Actual (reported)The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis. 75 patients were randomly assigned to the control, low-level laser and cryotherapy groups.Root canal treatments were performed in a single session. The pain intensity felt by the patients on the preoperative and postoperative 1st, 3rd, 5th and 7th days were recorded using the Wong Baker visual pain scale. Preoperative and postoperative 7th day percussion sensitivity was recorded using the VAS (visual analog scale) scale. The pain scores of the groups at different times after the procedure were compared. Statistical analysis of the data was performed at the 0.05 significance level.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 17, 2022
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 2, 2022
Actual (reported)June 3, 2022
Actual (reported)June 17, 2022
Actual (reported)July 19, 2022
Actual (reported)July 27, 2022
Actual (reported)Wong Baker wong baker faces pain rating scale
Patient's current pain. Scores between 0 to 5. Higher score means worse outcome.
preoperative
Wong Baker wong baker faces pain rating scale
Patient's current pain. Scores between 0 to 5. Higher score means worse outcome.
postoperative (1st day)
Wong Baker wong baker faces pain rating scale
Patient's current pain. Scores between 0 to 5. Higher score means worse outcome.
postoperative (3rd day)
After the carious tissue was removed and the endodontic cavity was opened, isolation was provided with a rubber-dam. After the canal length was determined with the Apex locater, the canals were prepared using Ni-Ti endodontic rotary instrument files at the torque value recommended by the manufacturer in an endodontic motor. Irrigation needles were kept 4-5 mm shorter than the working length, and irrigation of the channels was performed. A total of 5 ml of 1% NaOCl was washed for each canal, with 2 ml between each pecking movement of the files. The final washing of the channels was carried out using 5 ml of saline at room temperature.After the canals were dried with the help of a paper cone, the canals were filled by injecting iodoform and calcium hydroxide-containing canals. Then the restoration was completed with compomer.
After the carious tissue was removed and the endodontic cavity was opened, isolation was provided with a rubber-dam. After the canal length was determined with the Apex locater, the canals were prepared using Ni-Ti endodontic rotary instrument files at the torque value recommended by the manufacturer in an endodontic motor. A total of 5 ml of 1% NaOCl was washed for each canal, with 2 ml between each pecking movement of the files. The final washing of the channels was carried out using 5 ml of saline at room temperature.After the canals were dried with the help of a paper cone, the canals were filled by injecting iodoform and calcium hydroxide-containing canals. Then the restoration was completed with compomer. Following the restoration in the LLLT group, the diode laser was activated in biostimulation mode for a total of 1 minute, 30 seconds in the buccal and lingual/palatal regions at the root apex.
Root canal treatment
Root canal treatment+Laser application
Ataturk University Faculty of Dentistry
Erzurum, 25050, Turkey (Türkiye)
Gundogdu EC, Arslan H. Effects of Various Cryotherapy Applications on Postoperative Pain in Molar Teeth with Symptomatic Apical Periodontitis: A Preliminary Randomized Prospective Clinical Trial. J Endod. 2018 Mar;44(3):349-354. doi: 10.1016/j.joen.2017.11.002. Epub 2018 Feb 3.
Al-Nahlawi T, Hatab TA, Alrazak MA, Al-Abdullah A. Effect of Intracanal Cryotherapy and Negative Irrigation Technique on Postendodontic Pain. J Contemp Dent Pract. 2016 Dec 1;17(12):990-996.
Fatih Şengül, Phd
Atatürk Uni. Faculty of Dentistry
75 participants (actual enrollment reported by the registry).
Effect of Genetic Polymorphisms on Response to Preoperative NSAIDs in Endodontic Postoperative Pain Management
Wong Baker wong baker faces pain rating scale
Patient's current pain. Scores between 0 to 5. Higher score means worse outcome.
postoperative (5th day)
Wong Baker wong baker faces pain rating scale
Patient's current pain. Scores between 0 to 5. Higher score means worse outcome.
postoperative (7th day)
Visual Analog Scale (VAS)
Percussion pain of tooth. Scores between 0 to 10. Higher score means worse outcome.
preoperative
Visual Analog Scale (VAS)
Percussion pain of tooth. Scores between 0 to 10. Higher score means worse outcome.
postoperative 7th day
After the carious tissue was removed and the endodontic cavity was opened, isolation was provided with a rubber-dam. After the canal length was determined with the Apex locater, the canals were prepared using Ni-Ti endodontic rotary instrument files at the torque value recommended by the manufacturer in an endodontic motor. Irrigation needles were kept 4-5 mm shorter than the working length, and irrigation of the channels was performed. A total of 5 ml of 1% NaOCl was washed for each canal, with 2 ml between each pecking movement of the files. The final washing of the channels was carried out using 5 ml of saline at room temperature. After the last wash, in the cryotherapy group, unlike the first two groups, each canal was washed with 5 ml of 2°C cold physiological saline for 5 minutes. After the canals were dried with the help of a paper cone, the canals were filled by injecting iodoform and calcium hydroxide-containing canals. Then the restoration was completed with compomer.
Root canal treatment + Cryotherapy application
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Lopes LPB, Herkrath FJ, Vianna ECB, Gualberto Junior EC, Marques AAF, Sponchiado Junior EC. Effect of photobiomodulation therapy on postoperative pain after endodontic treatment: a randomized, controlled, clinical study. Clin Oral Investig. 2019 Jan;23(1):285-292. doi: 10.1007/s00784-018-2435-9. Epub 2018 Apr 16.
Arslan H, Doganay E, Karatas E, Unlu MA, Ahmed HMA. Effect of Low-level Laser Therapy on Postoperative Pain after Root Canal Retreatment: A Preliminary Placebo-controlled, Triple-blind, Randomized Clinical Trial. J Endod. 2017 Nov;43(11):1765-1769. doi: 10.1016/j.joen.2017.06.028. Epub 2017 Sep 28.
First Submitted
July 19, 2022
First Posted
July 27, 2022
Study Start
May 2, 2022
Actual (reported)Primary Completion
June 3, 2022
Actual (reported)Study Completion
June 17, 2022
Actual (reported)Last Updated
July 29, 2022
Record last verified: 2022-07
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: