NCT05472909

Brief Summary

The purpose of this study is to examine if patients have a lower anxiety level during wide awake hand surgery while listening to their choice of music vs standardized relaxation music. Patients who are planning to undergo wide awake (local anesthetic only hand surgery) and agree to participate will be randomized to either a music intervention where they listen to their choice of music genre or standardized relaxation music during their time in the operating room. 170 participants will be enrolled and can expect to be on study for 2 weeks.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
170

participants targeted

Target at P75+ for not_applicable anxiety

Timeline
12mo left

Started Jul 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 21, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 25, 2022

Completed
3.9 years until next milestone

Study Start

First participant enrolled

July 1, 2026

Expected
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2027

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2027

Last Updated

April 30, 2026

Status Verified

October 1, 2025

Enrollment Period

1 year

First QC Date

July 21, 2022

Last Update Submit

April 24, 2026

Conditions

Keywords

wide-awake hand surgerymusic interventionpatient care

Outcome Measures

Primary Outcomes (2)

  • Change in Visual Analog Scale-Anxiety (VAS-A) Score

    The VAS-A is scored from 0-10 where 0 is 'feeling calm' and 10 is 'extremely anxious'.

    day 0 post-operative, up to day 14

  • Change in State Trait Anxiety Inventory (STAI) Score

    The STAI is a 20-item questionnaire (form Y-1) scored on a 4 point likert scale where 1 is 'not at all', 2 is 'somewhat', 3 is 'moderately so', and 4 is 'very much so' for a total possible range of scores from 20-80 where higher scores indicate increased anxiety.

    day 0 post-operative, up to day 14

Secondary Outcomes (4)

  • Participant Heart Rate

    day 0, pre- and intraoperative

  • Participant Systolic Blood Pressure

    pre- and intraoperative on day 0

  • Participant Diastolic Blood Pressure

    pre- and intraoperative on day 0

  • Participant Respiratory Rate

    pre- and intraoperative on day 0

Study Arms (2)

Standardized Relaxation Music

EXPERIMENTAL
Other: Standardized Relaxation Music

Personal Choice of Music

ACTIVE COMPARATOR
Other: Personal Choice of Music

Interventions

Participants listen to their preferred music during surgery.

Personal Choice of Music

Participants listen to standardized relaxation music during surgery.

Standardized Relaxation Music

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult (18 years of age or older) patients
  • Undergoing Wide Awake Local Anesthesia No Tourniquet (WALANT) hand surgery

You may not qualify if:

  • Patients under the age of 18
  • Patients unable to consent for themselves
  • Patients unwilling to consent
  • Non-English speaking patients
  • Patients with significant hearing impairment not able to be corrected with assistive devices

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Wisconsin

Madison, Wisconsin, 53705, United States

RECRUITING

Related Publications (5)

  • Kuhlmann AYR, de Rooij A, Kroese LF, van Dijk M, Hunink MGM, Jeekel J. Meta-analysis evaluating music interventions for anxiety and pain in surgery. Br J Surg. 2018 Jun;105(7):773-783. doi: 10.1002/bjs.10853. Epub 2018 Apr 17.

    PMID: 29665028BACKGROUND
  • Palmer JB, Lane D, Mayo D, Schluchter M, Leeming R. Effects of Music Therapy on Anesthesia Requirements and Anxiety in Women Undergoing Ambulatory Breast Surgery for Cancer Diagnosis and Treatment: A Randomized Controlled Trial. J Clin Oncol. 2015 Oct 1;33(28):3162-8. doi: 10.1200/JCO.2014.59.6049. Epub 2015 Aug 17.

    PMID: 26282640BACKGROUND
  • Bradt J, Dileo C, Shim M. Music interventions for preoperative anxiety. Cochrane Database Syst Rev. 2013 Jun 6;2013(6):CD006908. doi: 10.1002/14651858.CD006908.pub2.

    PMID: 23740695BACKGROUND
  • Feneberg AC, Kappert MB, Maidhof RM, Doering BK, Olbrich D, Nater UM. Efficacy, Treatment Characteristics, and Biopsychological Mechanisms of Music-Listening Interventions in Reducing Pain (MINTREP): Study Protocol of a Three-Armed Pilot Randomized Controlled Trial. Front Psychiatry. 2020 Nov 4;11:518316. doi: 10.3389/fpsyt.2020.518316. eCollection 2020.

    PMID: 33329075BACKGROUND
  • Mitchell LA, MacDonald RA. An experimental investigation of the effects of preferred and relaxing music listening on pain perception. J Music Ther. 2006 Winter;43(4):295-316. doi: 10.1093/jmt/43.4.295.

    PMID: 17348757BACKGROUND

MeSH Terms

Conditions

Anxiety Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Officials

  • Lisa Kruse, MD

    University of Wisconsin, Madison

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 21, 2022

First Posted

July 25, 2022

Study Start (Estimated)

July 1, 2026

Primary Completion (Estimated)

July 1, 2027

Study Completion (Estimated)

July 1, 2027

Last Updated

April 30, 2026

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will not share

Results will not be shared with patients or their primary care physicians. Study results will be shared via manuscript publication in a peer reviewed journal. Data will be pooled and deidentified. No individual results will be shared.

Locations