NCT05470751

Brief Summary

Male self catherterisng observational study.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
72

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2023

Geographic Reach
3 countries

16 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 20, 2022

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 22, 2022

Completed
7 months until next milestone

Study Start

First participant enrolled

February 2, 2023

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 6, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 6, 2024

Completed
Last Updated

April 30, 2024

Status Verified

April 1, 2024

Enrollment Period

1.2 years

First QC Date

July 20, 2022

Last Update Submit

April 29, 2024

Conditions

Keywords

neurogenic bladderintermittent self-catherterisationpainbladder outflow obstruction

Outcome Measures

Primary Outcomes (1)

  • To assess difficulty during catheterisation and quality of life using the ICDQ and ISC-Q validated questionnaires during catheterisation

    To assess difficulty during catheterisation and quality of life using the ICDQ and ISC-Q

    60 days

Secondary Outcomes (2)

  • To assess patient confidence regarding reduced stickiness plus related risk of urethral injury and resultant bleeding or infection

    60 days

  • To assess compliance with the self-catheterization for the study duration

    60 days

Interventions

Self-catheterising with GC Male and Glide Male with Feelclean technology

Eligibility Criteria

Age18 Years - 100 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsMust be able to insert catheter into a penile urethra
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult males who self-catheterise

You may qualify if:

  • Adult male (aged 18 years and over)
  • Diagnosed with a neurological lower urinary tract dysfunction due to either spinal cord injury, Multiple Sclerosis, Parkinson's Syndrome, Cauda equina syndrome Or Diagnosed with bladder outflow obstruction secondary to benign prostate enlargement Or Diagnosed with detrusor underactivity
  • Performing single use clean intermittent self-catheterisation (ISC) at least twice a day
  • Willing to undergo training with GC Trainer video prior to use of catheter
  • Provided fully informed consent and has sufficient understanding of English or French
  • Sufficient dexterity to use GentleCath™ Air for Men intermittent including ability to open packaging
  • Intact urethral sensation of catheterisation
  • Willing to use only the GentleCath™ Air intermittent catheter for the full duration of the study (60-days)
  • Subject has a valid email address so the Investigator can send links to study questionnaires and the subject has access to a web enabled device

You may not qualify if:

  • Participation in another related urological study
  • Unable to perform ISC unaided
  • Already prescribed the GentleCath™ Air Intermittent Catheter
  • Absent urethral or perineal sensation
  • Unwilling to undergo training with GC Trainer prior to use of catheter
  • Insufficient dexterity to use GentleCath™ Air Intermittent Catheter and or packaging
  • Undergoing surgical treatment during the period of the study
  • Performing catheterisation for urethral stricture

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (16)

Kessler Institute for Rehabilitation

West Orange, New Jersey, 07052, United States

Location

Trustees of The University of Pennsylvania | Penn Urology Washington Square

Philadelphia, Pennsylvania, 19106, United States

Location

Centre Hospitalier Universitaire de Bordeaux | Pellegrin Hospital - Urology Department

Bordeaux, 33076, France

Location

Assistance Publique Hopitaux de Paris | Pitie Salpetriere University Hospital - Urology Department

Paris, 75013, France

Location

Stockport NHS Foundation Trust | Stepping Hill Hospital - Research and Innovation Department

Stockport, Cheshire, SK2 7JE, United Kingdom

Location

Broomfield Hospital

Chelmsford, Essex, CM1 7ET, United Kingdom

Location

Mid and South Essex NHS Foundation Trust | Southend University Hospital - Research & Development

Southend-on-Sea, Essex, SS0 0RY, United Kingdom

Location

Aneurin Bevan University Health Board | Royal Gwent Hospital - Clinical Research Centre

Newport, Gwent, NP20 2UB, United Kingdom

Location

Southampton General Hospital

Southampton, Hampshire, SO16 6YD, United Kingdom

Location

Kent and Canterbury Hospital | Renal Research Delivery Team

Canterbury, Kent, CT2 7FG, United Kingdom

Location

Newcastle upon Tyne Hospitals NHS Foundation Trust | Freeman Hospital - Urology Department

Newcastle, Newcastle Upon Tyne, NE7 7DN, United Kingdom

Location

Sunderland Royal Hospital

Sunderland, Tyne & Wear, SR4 7TP, United Kingdom

Location

North Bristol NHS Trust | Southmead Hospital - Research and Development - Urology Department

Bristol, Westbury-on-Trym, BS10 5NB, United Kingdom

Location

Mid Yorkshire Teaching NHS Trust | Pinderfields Hospital - Yorkshire Regional Spinal Injuries Centre

Wakefield, Yorkshire, WF1 4DG, United Kingdom

Location

Guy's and St Thomas' Foundation Trust | Guy's Hospital - Transplant, Renal and Urology Research

London, SE1 9RT, United Kingdom

Location

King's College Hospital NHS Foundation Trust | King's College Hospital - Renal Research Department

London, SE5 9RS, United Kingdom

Location

MeSH Terms

Conditions

Urinary Bladder Neck ObstructionMultiple SclerosisCauda Equina SyndromeParkinson DiseaseLower Urinary Tract SymptomsUrinary Bladder, UnderactiveSpinal Cord InjuriesUrinary Bladder, NeurogenicPain

Condition Hierarchy (Ancestors)

Urethral ObstructionUrethral DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesUrinary Bladder DiseasesMale Urogenital DiseasesDemyelinating Autoimmune Diseases, CNSAutoimmune Diseases of the Nervous SystemNervous System DiseasesDemyelinating DiseasesAutoimmune DiseasesImmune System DiseasesNerve Compression SyndromesPeripheral Nervous System DiseasesNeuromuscular DiseasesPolyradiculoneuropathyPolyneuropathiesParkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative DiseasesUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsSpinal Cord DiseasesTrauma, Nervous SystemWounds and InjuriesNeurologic Manifestations

Study Officials

  • Chris Harding

    Site Investigator - Newcastle

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 20, 2022

First Posted

July 22, 2022

Study Start

February 2, 2023

Primary Completion

April 6, 2024

Study Completion

April 6, 2024

Last Updated

April 30, 2024

Record last verified: 2024-04

Data Sharing

IPD Sharing
Will not share

Locations