Epidemiological Characteristics and Outcomes of Patients Admitted to Kenyan Critical Care Units (EPOK).

NCT05456217 | Unknown

• 1 other identifier: CCAA-K-1-22
• Study Type: observational
• Target: 4,000
• Locations: 1 country
• Sites: 6

Brief Summary

The Kenyan Critical Care Registry was started in December 2020 and currently involves 10 critical care units in 6 Hospitals. As an initial registry output, we aim to describe patient epidemiological characteristics, initial management and outcomes of critically ill patients in Kenya. This project will provide a much-needed source of clinico-demographic and outcomes data for participating Kenyan critical care units. It will also help to identify processes and outcomes which can be targeted by quality improvement projects, the impact of which can then be evaluated later using the registry.

Conditions

Outcome Studies; Mechanical Ventilation; Kenya

Outcome Measures

Primary Outcomes (4)

• ICU mortality

  death during ICU or HDU stay

  1 month

• Length of ICU stay

  duration of stay in the ICU or HDU in days

  1 month

• Demographic characteristics

  The following demographic characteristics are collected: age, sex

  ICU admission

• APACHE 2 score

  Acute Physiology and Chronic Evaluation 2 score

  ICU admission

Secondary Outcomes (6)

• Patients receiving mechanical ventilation

  1 month

• Tracheostomy rate

  1 month

• Reason for admission

  ICU admission - first 24h

• Use of vasopressors

  ICU admission - first 24h

• Use of sedatives

  ICU admission - first 24h

Interventions

admission to ICU OTHER

admission to an intensive care unit or high dependency unit in Kenya

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Consecutive patients admitted to ICUs or HDUs participating in the Kenya Critical Care registry

You may qualify if:

• Admitted to an intensive care unit or high dependency unit
• Included in the Kenya Critical Care registry platform

You may not qualify if:

• None

Sponsors & Collaborators

• Nat Intensive Care Surveillance - MORU: lead
• Critical Care Society of Kenya: collaborator

Study Sites (6)

Kisii County Hospital

Kisii, Kenya

RECRUITING

Mombasa Aga Khan Hospital

Mombasa, Kenya

RECRUITING

Aga Khan University Hospital

Nairobi, Kenya

RECRUITING

MP Shah Hospital

Nairobi, Kenya

RECRUITING

Nakuru level V Hospital

Nakuru, Kenya

RECRUITING

Nyeri County Hospital

Nyeri, Kenya

RECRUITING

Related Publications (2)

• Pisani L, Waweru-Siika W, Sendagire C, Beane A, Haniffa R. Critically ill COVID-19 patients in Africa: it is time for quality registry data. Lancet. 2021 Aug 7;398(10299):485-486. doi: 10.1016/S0140-6736(21)01549-X. No abstract available.

  PMID: 34364515 BACKGROUND

• Njoki C, Simiyu N, Kaddu R, Mwangi W, Sulemanji D, Oduor P, Dona DG, Otieno D, Abonyo TT, Wangeci P, Kabanya T, Mutuku S, Kioko A, Muthoni J, Kamau PM, Beane A, Haniffa R, Dondorp A, Misango D, Pisani L, Waweru-Siika W. EPidemiology, clinical characteristics and Outcomes of 4546 adult admissions to high-dependency and intensive care units in Kenya (EPOK): a multicentre registry-based observational study. Crit Care Explor. 2024 Feb 1;6(2):e1036. doi: 10.1097/CCE.0000000000001036. eCollection 2024 Feb 1.

  PMID: 38356864 DERIVED

Central Study Contacts

Wangari Siika, Prof.

CONTACT

+254 708 612258; wangari.siika@aku.edu

Carolyne Njoki, Dr

CONTACT

+254 720 562416; njokimuiru@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 4 Weeks
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 11, 2022
• First Posted: July 13, 2022
• Study Start: January 1, 2021
• Primary Completion: August 1, 2022
• Study Completion: September 1, 2022
• Last Updated: July 13, 2022

Record last verified: 2022-07

Locations

KE (6)