NCT05455892

Brief Summary

Since the beginning of the year 2020, clinical characteristics of a new disease as the global COVID-19 epidemic has spread in France. People over 70 years of age are the more concerned by this virus in proportion and in gravity with some atypical first symptoms compared to younger patients. Evolution of the disease is variable from forms with few symptoms to severe forms sometimes quickly lethal. GERICOVID LYON is a descriptive analysis of all patients over 70 years of age hospitalised for COVID-19 in short geriatric unities of University Hospital of Lyon This study will allow more comprehension about COVID-19 in older people. The role of predictive factors, pre-existing comorbidities and the nature and frequency of complications in a short period will be investigate. Treatments practices will be analysed too.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
450

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2020

Typical duration for all trials

Geographic Reach
1 country

5 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 23, 2020

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2021

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

July 11, 2022

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 13, 2022

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2022

Completed
Last Updated

July 20, 2022

Status Verified

July 1, 2022

Enrollment Period

1.3 years

First QC Date

July 11, 2022

Last Update Submit

July 18, 2022

Conditions

Keywords

ELDERLYCOVID-19

Outcome Measures

Primary Outcomes (1)

  • In hospital mortality rate.

    Observed mortality rate will be presented with its 95% confidence interval.

    During patient hospitalization, an average of 10 days.

Study Arms (1)

Elder patients hospitalized for COVID-19 in geriatric short stay units.

All patients over 70 years of age, with a positive Polymerase Chain Reaction or a high presumption of COVID-19, hospitalized in short geriatric units in University Hospital of Lyon, who agree with retrospective collection of their clinical datas.

Other: Clinical data collection during hospitalization in short geriatric units.

Interventions

Retrospective clinical data collection, at time of infection and 10 days later. Correlation between mortality and gravity. Identification of predictive mortality factors such as frailty, preexisting comorbidities, complications and treatments. Description of medical prescription evolutions.

Elder patients hospitalized for COVID-19 in geriatric short stay units.

Eligibility Criteria

Age70 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study was proposed to all patients over 70 years of age, with a positive Polymerase Chain Reaction or a high presumption of COVID-19, hospitalized in short geriatric units in University Hospital of Lyon between 1er March 2020 and 30th June 2020.

You may qualify if:

  • Patient over 70 years of age.
  • Patient hospitalized in short geriatric units in University Hospital of Lyon.
  • Patient diagnosed with COVID-19 (positive Polymerase Chain Reaction or a high presumption of COVID-19 based on clinical and/or scannographic evidence).
  • Patient Informed and non-opposed to the research (Patient informed of the study by his medical doctor during hospitalization or by post, thanks to a generic information sheet dedicated to COVID-19 researches).

You may not qualify if:

  • Patient opposed to the research.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Service de gériatrie aigue de l'hôpital de la Croix Rousse. Hospices Civils de Lyon

Caluire-et-Cuire, Rhone, 69300, France

Location

Service de gériatrie aigue de l'hôpital Edouard Herriot, Pavillon T. Hospices Civils de Lyon

Lyon, Rhone, 69003, France

Location

Service de gériatrie aigue de l'hôpital Edouard Herriot. Hospices Civils de Lyon

Lyon, Rhone, 69003, France

Location

Service de gériatrie aigue de l'hôpital Lyon Sud. Hospices Civils de Lyon

Pierre-Bénite, Rhone, 69495, France

Location

Service de gériatrie aigue de l'hôpital des Charpennes. Hospices Civils de Lyon

Villeurbanne, Rhone, 69100, France

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 11, 2022

First Posted

July 13, 2022

Study Start

July 23, 2020

Primary Completion

November 1, 2021

Study Completion

September 30, 2022

Last Updated

July 20, 2022

Record last verified: 2022-07

Locations