NCT05450874

Brief Summary

Develop and validate a novel scoring system based on pathological factors to predict the postoperative survival of patients with rHCC.Patients with rHCC who underwent hepatectomy were recruited from two hospitals.Exploring whether this scoring system is related to prognosis

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2010

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2010

Completed
7.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2017

Completed
5.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2022

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

July 5, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

July 11, 2022

Completed
Last Updated

July 11, 2022

Status Verified

June 1, 2022

Enrollment Period

7.1 years

First QC Date

July 5, 2022

Last Update Submit

July 8, 2022

Conditions

HCC

Outcome Measures

Primary Outcomes (1)

  • overall survival

    Time from the first postoperative day to survival at the last follow-up

    2010-2022

Study Arms (2)

Training cohort

Procedure: hepatectomy

Validation cohort

Procedure: hepatectomy

Interventions

hepatectomyPROCEDURE
Training cohortValidation cohort

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

A total of 221 patients with rHCC who underwent liver resection from February 2010 to March 2016 at Tongji Hospital and 97 patients with rHCC who underwent hepatectomy at Zhongshan People's Hospital during the same period were included in this study

You may qualify if:

  • a diagnosis of ruptured tumor confirmed by enhanced computed tomography (CT) and/or abdominal magnetic resonance imaging (MRI),
  • a diagnosis of HCC made by two experienced pathologists

You may not qualify if:

  • extrahepatic HCC metastasis
  • death within 1 month after surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Hepatectomy

Intervention Hierarchy (Ancestors)

Digestive System Surgical ProceduresSurgical Procedures, Operative

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 5, 2022

First Posted

July 11, 2022

Study Start

February 1, 2010

Primary Completion

March 1, 2017

Study Completion

June 1, 2022

Last Updated

July 11, 2022

Record last verified: 2022-06