NCT05450588

Brief Summary

The assessment of body composition is one of the main components within the evaluation of nutritional status under the ABCDE model. Generally, the use of equations to estimate components is a frequent strategy since it represents a doubly indirect method that has good correlation with methods of higher sensitivity (i.e., NMR, DXA, etc.). In this sense, the waist girth or circumference (WC) represents a quick, simple and inexpensive tool to evaluate the excess of fat mass in the human being; however, this measurement does not provide information on body composition in isolation and has been used as an important independent variable in some recent equations (e.g., relative fat mass \[RFM\]). Considering the lack of formulas or external validation of RFM in the Colombian population, the aim of this STROBE-Nut-based cross-sectional study is to develop and validate simple equations that use WC as an independent variable to estimate fat mass and fat-free mass in a population with different physical activity levels.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
130

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 5, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 8, 2022

Completed
1.6 years until next milestone

Study Start

First participant enrolled

March 1, 2024

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2024

Completed
Last Updated

September 11, 2023

Status Verified

September 1, 2023

Enrollment Period

Same day

First QC Date

July 5, 2022

Last Update Submit

September 7, 2023

Conditions

Keywords

Body compositionWaist GirthRegression EcuationsFat massFat free mass

Outcome Measures

Primary Outcomes (1)

  • Two-component model of body composition (fat mass and free mass)

    Through DXA measurement and the estimation using anthropometry-based equations.

    One year (March 2024 to June 2024)

Secondary Outcomes (1)

  • Anthropometry-based morphological

    One year (March 2024 to June 2024)

Study Arms (3)

Sedentary

It will be obtained by open call for both students and administrative staff at the CES University.

Physically active

Under the collaboration framework bet ween DBSS international SAS and Smart Fit Colombia, a sample of personal trainers who reside and work in Medellín, or its metropolitan area will be invited to participate.

Athletes

Under the collaboration framework between DBSS international SAS and ARTHROS Physiotherapy and Exercise Center, a sample of professional athletes from different sports disciplines will be invited to participate.

Eligibility Criteria

Age18 Years - 59 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

According to previous recommendations (Knofczynski and Mundfrom,2007), 130 participants will be needed to obtain a coefficient of determination (R2) of 0.5 with an excellent level of prediction and with three independent variables. The subjects will be divided into three groups for validation and development of the new equations, the total number of participants will be divided into 3 strata following optimal allocation methods. Assigned a fixed cost for each stratum (sedentary people, C1; physically active subjects, C2; and sportsmen, C3, given that C3\>C2\>C1).The values obtained for the sedentary group were n=54, the physically active population group n= 43, and the sportsmen group n=33. In the new equation, the development/validation ratio will be 70/30 over the number of subjects.

You may qualify if:

  • +18 years old (under 60 years)
  • Sedentary, Physically active and Athletes of competitive level.
  • Residing in the city of Medellín or nearby municipalities of the metropolitan area.
  • Signed informed consent.
  • Assist to anthropometric and DXA measurements.

You may not qualify if:

  • People with a disease and/or special condition that limits exposure to radiation emitted by DXA.
  • Adults over 60 years of age
  • Pregnant women
  • Athletes with injuries
  • People with implants or prostheses.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ces Nutral

Medellín, Antioquia, 050001, Colombia

Location

Related Publications (1)

  • Bonilla DA, Duque-Zuluaga LT, Munoz-Urrego LP, Moreno Y, Velez-Gutierrez JM, Franco-Hoyos K, Agudelo-Martinez A, Humeres G, Kreider RB, Petro JL. Development and Validation of Waist Girth-Based Equations to Evaluate Body Composition in Colombian Adults: Rationale and STROBE-Nut-Based Protocol of the F20 Project. Int J Environ Res Public Health. 2022 Aug 27;19(17):10690. doi: 10.3390/ijerph191710690.

Related Links

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Diego A Bonilla, PhD

    Research Division, DBSS International SAS.

    PRINCIPAL INVESTIGATOR
  • Jorge L Petro, PhD

    Research Division, DBSS International SAS.

    STUDY CHAIR
  • Laura P Muñoz, MSc

    Grupo de Investigación Nutral, Facultad Ciencias de la Nutrición y los Alimentos, Universidad CES.

    STUDY DIRECTOR
  • Leidy T Duque, MSc

    Grupo de Investigación Nutral, Facultad Ciencias de la Nutrición y los Alimentos, Universidad CES.

    STUDY DIRECTOR

Central Study Contacts

Diego A Bonilla, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 5, 2022

First Posted

July 8, 2022

Study Start

March 1, 2024

Primary Completion

March 1, 2024

Study Completion

June 1, 2024

Last Updated

September 11, 2023

Record last verified: 2023-09

Data Sharing

IPD Sharing
Will not share

Locations