Evaluation of Thromboprophylaxis Appropriateness in Hospitalized Medical Patients

NCT05449808 | Unknown DMC

• 1 other identifier: Venous thromboprophylaxis
• Study Type: observational
• Target: 320
• Locations: 1 country
• Sites: 1

Brief Summary

Considering observational studies that suggested a relationship between acutely ill medical patients and venous thromboembolism (VTE), interventional studies with anticoagulant medications indicated a marked decline in VTE during and after hospitalization. Despite the therapeutic value of lowering this result, there is a low inclination to utilize anticoagulants in patients hospitalized for acute medical diseases. This observational research aims to assess the appropriateness of venous thromboprophylaxis offered to patients admitted to internal medicine wards.

Conditions

Deep Vein Thrombosis; Pulmonary Embolism; Venous Thromboses

Keywords

Padua prediction score; Pulmonary Embolism; Deep Vein Thrombosis; Venous Thromboses; Acute medical illness

Outcome Measures

Primary Outcomes (1)

• Appropriateness of venous thromboprophylaxis

  The primary outcome of this study is to evaluate the appropriateness of venous thromboprophylaxis administered to medical inpatients who need pharmacologic interventions according to the American College of Chest Physicians (ACCP) 2012 guidelines and its second update in 2021.

  August - December 2022

Secondary Outcomes (1)

• Reasons for insufficient venous thromboprophylaxis

  August - December 2022

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Baghdad medical city; general internal medicine divisions patients'

You may qualify if:

• Age ≥18 years
• Hospitalized for any cause in the internal medicine ward
• Ability to give informed consent, as informed by the physicians in charge of the patient

You may not qualify if:

• Expected hospital stay \< 48 h
• Patients unable to give informed consent, as informed by the physicians in charge of the patient
• Patients with therapeutic anticoagulation at hospital admission
• Patients admitted for a disease requiring therapeutic anticoagulation
• Patients admitted to non-medical hospital wards

Sponsors & Collaborators

• Al-Esraa University College: lead

Study Sites (1)

EUC

Baghdad, 10011, Iraq

RECRUITING

Related Publications (2)

• Haas SK. Venous thromboembolic risk and its prevention in hospitalized medical patients. Semin Thromb Hemost. 2002 Dec;28(6):577-84. doi: 10.1055/s-2002-36702.

  PMID: 12536351 BACKGROUND

• Barbar S, Noventa F, Rossetto V, Ferrari A, Brandolin B, Perlati M, De Bon E, Tormene D, Pagnan A, Prandoni P. A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score. J Thromb Haemost. 2010 Nov;8(11):2450-7. doi: 10.1111/j.1538-7836.2010.04044.x.

  PMID: 20738765 BACKGROUND

MeSH Terms

Conditions

Venous Thrombosis; Pulmonary Embolism

Condition Hierarchy (Ancestors)

Thrombosis; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases; Lung Diseases; Respiratory Tract Diseases; Embolism

Study Officials

• Khulood M. Alsaraf, ASST PROF

  Al-Esraa University College

  STUDY CHAIR

Central Study Contacts

Laith G. Shareef, F.I.B.M.S.

CONTACT

009647702884263; laith-shareef@esraa.edu.iq

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director

Study Record Dates

• First Submitted: July 5, 2022
• First Posted: July 8, 2022
• Study Start: November 13, 2022
• Primary Completion: February 1, 2023
• Study Completion: February 1, 2023
• Last Updated: October 24, 2022

Record last verified: 2022-10

Locations

IR (1)