Abdominal Aortic Aneurysm Screening Before Coronary Artery Bypass Surgery

NCT05449509 | Unknown

• 1 other identifier: KAEK/2022.02.43
• Study Type: observational
• Target: 170
• Locations: 1 country
• Sites: 1

Brief Summary

Coronary artery disease (CAD) and abdominal aortic aneurysm (AAA) are two separate entities with common risk factors such as hypertension, advanced age, male sex. Atherosclerosis plays an important role in the etiology of both diseases. It has been reported that AAA is more prevalent in patients undergoing coronary artery bypass grafting (CABG). Despite all the evidence, current guidelines do not recommend routine screening for AAA before CABG. Syntax score shows anatomical significance of CAD and is associated with the degree of atherosclerotic load. The investigators aim to investigate if there were any differences regarding AAA prevalence in high-SYNTAX patients versus intermediate/low-SYNTAX patients.

Conditions

Coronary Artery Disease; Abdominal Aortic Aneurysm

Outcome Measures

Primary Outcomes (1)

• Infrarenal abdominal aortic diameter

  Infrarenal abdominal aortic diameter measured by bedside Duplex ultrasound by the principal investigator, Dr. Ozeren-Topcu

  Baseline

Study Arms (2)

High-SYNTAX score patients

Diagnostic Test: Abdominal aortic Duplex ultrasound

Intermediate/low-SYNTAX score patients

Diagnostic Test: Abdominal aortic Duplex ultrasound

Interventions

Abdominal aortic Duplex ultrasound DIAGNOSTIC_TEST

All patients will undergo bedside Duplex ultrasound in order to measure infrarenal abdominal aortic diameter.

High-SYNTAX score patients; Intermediate/low-SYNTAX score patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Consecutive adult patients undergoing elective CABG in the Department of Cardiovascular Surgery in Basaksehir Cam Sakura City Hospital

You may qualify if:

• Undergoing coronary artery bypass graft surgery
• Age \>18 years

You may not qualify if:

• Age \<18 years
• Pregnancy
• Breastfeeding
• Emergency surgery

Sponsors & Collaborators

• Başakşehir Çam & Sakura City Hospital: lead

Study Sites (1)

Basaksehir Cam ve Sakura City Hospital

Istanbul, Turkey (Türkiye)

RECRUITING

Related Publications (2)

• Bergersen L, Kiernan MS, McFarlane G, Case TD, Ricci MA. Prevalence of abdominal aortic aneurysms in patients undergoing coronary artery bypass. Ann Vasc Surg. 1998 Mar;12(2):101-5. doi: 10.1007/s100169900124.

  PMID: 9514225 BACKGROUND

• Yammine M, Itagaki S, Pawale A, Toyoda N, Reddy RC. SYNTAX score may predict the severity of atherosclerosis of the ascending aorta. J Thorac Dis. 2017 Oct;9(10):3859-3865. doi: 10.21037/jtd.2017.09.17.

  PMID: 29268395 BACKGROUND

MeSH Terms

Conditions

Coronary Artery Disease; Aortic Aneurysm, Abdominal

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Aortic Aneurysm; Aneurysm; Aortic Diseases

Central Study Contacts

Kamile Ozeren-Topcu, MD

CONTACT

902129096000; kammileozeren@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 2, 2022
• First Posted: July 8, 2022
• Study Start: August 15, 2022
• Primary Completion: August 15, 2023
• Study Completion: August 30, 2023
• Last Updated: February 14, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)