NCT05443204

Brief Summary

Evaluation of Glycemic Control by Flash Monitoring of Glucose (MFG) in Malnourished Patients With Type 2 Diabetes (MFG SNO)

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 29, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

July 5, 2022

Completed
2 days until next milestone

Study Start

First participant enrolled

July 7, 2022

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2023

Completed
Last Updated

October 7, 2022

Status Verified

May 1, 2022

Enrollment Period

6 months

First QC Date

June 29, 2022

Last Update Submit

October 6, 2022

Conditions

Keywords

Diabetes type 2MalnutritionMFG

Outcome Measures

Primary Outcomes (5)

  • MFG discharge - mean interstitial glucose

    Interstitial glucose measured in mg/dl

    During 14 days after taking the supplement

  • MFG discharge - hyperglycaemia

    hyperglycaemia measured in mg/dl

    During 14 days after taking the supplement

  • MFG discharge - hypoglycaemia

    hypoglycaemia measured in mg/dl

    During 14 days after taking the supplement

  • MFG discharge - GMI

    Measured in number of scans per day

    During 14 days after taking the supplement

  • MFG discharge - hypoglycaemic events

    Measured in number and duration per day

    During 14 days after taking the supplement

Secondary Outcomes (1)

  • Postprandial glucose intersticial monitoringdiabetes specific supplement

    During the 4 hours after taking standard formula and the one specific for diabetes

Study Arms (2)

Standard Formula (Fortimel)

EXPERIMENTAL

Fats 35% total caloric volume (VCT) Carbohydrates: 49% del VCT Proteins: 16% del VCT Density: 1.5 kcal/ ml

Other: Fortimel energy

Specific formula for diabetes (Nutrision Advanced)

EXPERIMENTAL

Fats: 46% del VCT (60% monounsaturated fatty acids) Carbohydrates: 31% del VCT Proteins: 21% del VFiber: 2% VCT (80% soluble y 20% insoluble) Density: 1.5kcal/ml

Other: Nutrision Advanced Diason Energy HP

Interventions

Standard nutritional oral supplement

Standard Formula (Fortimel)

Specifc nutritional oral supplement in diabetics patients

Specific formula for diabetes (Nutrision Advanced)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with DM2 under follow-up by the Clinical Nutrition and Dietetics Unit (UNCYD) who present malnutrition or are at risk of malnutrition and require oral nutritional supplements, for a minimum estimated period of 3 months.

You may not qualify if:

  • Patients with DM1, steroid diabetes, pancreatic diabetes, DM2 treated with rapid insulin, glomerular filtration rate less than 30 mL/min/1.73m2, intolerance to the product, gastrectomy or gastroparesis.
  • Patients who do not sign the consent informed.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Regional Universitario de Málaga

Málaga, 29010, Spain

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Malnutrition

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesNutrition Disorders

Study Officials

  • Gabriel Olveira Fuster, MD, PhD.

    Hospital Regional Universitario de Málaga - FIMABIS

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Viyey Kishore Doulatram Gamgaram, MD, PhD.

CONTACT

Gabriel Olveira Fuster, MD, PhD.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Patients will be assigned in a 1:1 ratio
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 29, 2022

First Posted

July 5, 2022

Study Start

July 7, 2022

Primary Completion

December 31, 2022

Study Completion

May 31, 2023

Last Updated

October 7, 2022

Record last verified: 2022-05

Locations