NCT05442723

Brief Summary

Diseased left Anterior descending coronary artery (LAD) is one of the most challenging conditions in Bypass surgery. we investigate whether on-pump coronary artery bypass grafting (CABG) is more beneficial in those critical patients or off-pump surgery.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 25, 2022

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

February 26, 2022

Completed
4 months until next milestone

First Posted

Study publicly available on registry

July 5, 2022

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 24, 2023

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2023

Completed
Last Updated

July 5, 2022

Status Verified

June 1, 2022

Enrollment Period

12 months

First QC Date

February 26, 2022

Last Update Submit

June 28, 2022

Conditions

CAD - Coronary Artery Disease

Keywords

On-pumpoff-pumpCABGLAD

Outcome Measures

Primary Outcomes (2)

  • mortality

    follow up post-operative track of the patient for any noticed mortality rate

    30 days post operative

  • Morbidity

    follow up post-operative track of the patient for any noticed complications

    60 days post operative

Study Arms (2)

Case

OTHER

Patients with extensive LAD disease treated with off-pump CABG

Procedure: Off-Pump CABG

Control

OTHER

Patients with extensive LAD disease treated with on-pump CABG

Procedure: On-Pump CABG

Interventions

On-Pump CABGPROCEDURE

coronary artery grafting by using cardiopulmonary bypass machine

Also known as: CABG
Control
Off-Pump CABGPROCEDURE

coronary artery grafting by beating heart technique

Case

Eligibility Criteria

Age30 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • any patient with diffuse LAD disease indicated for open heart surgery

You may not qualify if:

  • no concomitant valve disease
  • any patient can be treated by medical treatment or PCI

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Assiut university heart hospital

Asyut, 2112, Egypt

RECRUITING

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle investigator

Study Record Dates

First Submitted

February 26, 2022

First Posted

July 5, 2022

Study Start

February 25, 2022

Primary Completion

February 24, 2023

Study Completion

March 1, 2023

Last Updated

July 5, 2022

Record last verified: 2022-06

Locations

EG(1)