Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning

NCT05439330 | Recruiting

• 1 other identifier: 91340
• Study Type: interventional
• Target: 470
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional, dental-oriented radiographic images for diagnostic purposes.

Conditions

TMJ; Apical Periodontitis; Periodontal Inflammation; Retained Tooth; MRI

Outcome Measures

Primary Outcomes (1)

• Application of a dental-dedicated MRI in the diagnosis of temporomandibular joint disorders, tissue alterations related to third molars, periapical and periodontal inflammatory diseases, and implant treatment planning

  Diagnosis of pathologies in the TMJ (e.g. disc displacement (anterior/posterior/lateral), inflammation (yes/no), bone changes (yes/no)), periodontal defects (e.g. bone defects (mm), inflammation (yes/no)), periapical pathology (e.g. inflammation (yes/no), apical periodontitis (yes/no)), bone measurements in edentulous areas, and third molars (e.g. relation to surrounding structures (over/same level/under nerve), resorption of neighboring teeth (yes/no)) seen on MRI compared to diagnosis obtained in radiographs. Observations seen on MRI will be compared to observations seen in radiographs.

  2½ years

Study Arms (1)

Application of a dental-dedicated MRI

EXPERIMENTAL

MRI of conditions related to teeth and surrounding structures

Device: MRI of teeth and surrounding structures

Interventions

MRI of teeth and surrounding structures DEVICE

included above

Application of a dental-dedicated MRI

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• referred for CBCT imaging of at least one tooth for endodontic reasons
• referred for intra-oral and/or panoramic imaging covering at least one molar tooth for periodontal reasons
• referred for CBCT imaging of the TMJ (bilaterally)
• referred for panoramic imaging of the third molar (retained/semi-retained, uni- or bilateral), prior to treatment planning
• referred for CBCT imaging prior to implant treatment

You may not qualify if:

• younger than 18 years
• unable to give consent
• pregnant
• pronounced claustrophobia
• pacemakers or implanted defibrillators
• non-removable piercings

Sponsors & Collaborators

• University of Aarhus: lead
• Siemens Corporation, Corporate Technology: collaborator
• Dentsply Sirona Implants and Consumables: collaborator

Study Sites (1)

IOOS

Aarhus, 8000, Denmark

RECRUITING

MeSH Terms

Conditions

Periapical Periodontitis; Tooth, Impacted

Condition Hierarchy (Ancestors)

Periapical Diseases; Jaw Diseases; Stomatognathic Diseases; Periodontal Diseases; Mouth Diseases; Periodontitis; Tooth Diseases

Study Officials

• Rubens Spin-Neto, ph.D

  University of Aarhus

  STUDY CHAIR

Central Study Contacts

Rubens Spin-Neto, ph.D

CONTACT

+4587159713; rsn@dent.au.dk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: DDS, ph.d.

Model Details: Each person has a MRI scan done following the requested radiograph. MRI and radiographs are compared for diagnostic purposes.

Study Record Dates

• First Submitted: June 20, 2022
• First Posted: June 30, 2022
• Study Start: September 1, 2022
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: May 4, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

DK (1)