NCT05107232

Brief Summary

Optimization of magnetic resonance imaging (MRI) protocols on healthy volunteers and voluntary patients. In MRI, a large number of technical parameters (sequence, parameters in sequence, antenna, reconstruction method, etc.) can be changed to optimize the diagnostic quality of the exam. Some optimizations can be performed on participants healthy volunteers, others need to be carried out on images pathological and acquired in voluntary patients.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
600

participants targeted

Target at P75+ for not_applicable

Timeline
19mo left

Started Nov 2021

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress75%
Nov 2021Dec 2027

First Submitted

Initial submission to the registry

October 6, 2021

Completed
29 days until next milestone

First Posted

Study publicly available on registry

November 4, 2021

Completed
Same day until next milestone

Study Start

First participant enrolled

November 4, 2021

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2026

Expected
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2027

Last Updated

November 12, 2021

Status Verified

November 1, 2021

Enrollment Period

5 years

First QC Date

October 6, 2021

Last Update Submit

November 5, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Quality of MRI signal

    The quality of the images, maps or signals collected will be compared to standard acquisitions. This evaluation will be done by statistical comparison of visual qualitative criteria by expert radiologists or on quantitative criteria drawn from analyzes computing data obtained by processing experts images (signal-to-noise ratio, contrast-to-noise ratio, blur level, mutual information, co-location of regions highlighted by different techniques, etc.).

    15 days

Study Arms (1)

Participants

OTHER

Patients and Healthy volunteers included will have an MRI

Other: MRI

Interventions

MRIOTHER

MRI

Participants

Eligibility Criteria

Age6 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Criteria common to all participants:
  • Minor or major subject
  • Affiliated, himself or through his parents if he is a minor, to a a social security scheme
  • Having given their free, informed and written consent, and/or which the free, informed and written consent of the holder(s) parental authority has been obtained for minors
  • Specific criteria for healthy volunteers:
  • o No medical or surgical history related to the anatomical area(s) scanned
  • Specific criteria for voluntary patients:
  • o Indication for an MRI exam as part of its management

You may not qualify if:

  • \- Contraindication to an MRI (pacemaker or pacemaker, neurostimulator, intra-orbital metal body, vascular clip ferromagnetic)
  • Pregnancy
  • Legal protection measure for adults in progress (safeguard of justice, guardianship, curatorship) or subject deprived of liberty

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Rennes

Rennes, 35000, France

RECRUITING

Study Officials

  • Jean-Christophe FERRE, Pr

    CHU Rennes

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jean-Christophe Ferre, Pr

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 6, 2021

First Posted

November 4, 2021

Study Start

November 4, 2021

Primary Completion (Estimated)

November 1, 2026

Study Completion (Estimated)

December 1, 2027

Last Updated

November 12, 2021

Record last verified: 2021-11

Locations