Trials Sponsors Conditions Drugs Pricing

Conditions

Inflammatory Biomarkers Neutrophil-lymphocyte Ratio Posterior Reversible Encephalopathy Syndrome

Outcome Measures

Primary Outcomes (2)

inflammatory biomarkers
The values of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte-lymphocyte ratio will be measured.
Inflammatory biomarkers were collected within 1 day after the onset of symptoms.
cranial Imaging
According to the cranial Imaging, PE or E patients were grouped into PRES group (typical features presence of vasogenic edema in the white matter of the portions of both cerebral hemispheres) and NOT-PRES group (imaging findings were normal).
Cranial Imaging was examined within 3 days after the onset of symptoms, such as s headaches, visual changes, seizures, consciousness impairment.

Secondary Outcomes (3)

other biochemical parameters
biochemical parameters were collected within 1 week of the hospital stay.
Blood Pressure(BP)
The BP of patients was obtained within 1hour after the onset of symptoms.
pregnancy outcomes
The pregnancy outcomes will record immediately when the patients deliver.

Study Arms (2)

PRES group

patients in PE or E with PRES

Other: Whether the PE or E patient combined with PRES

NON-PRES group

patients in PE or E without PRES

Interventions

Whether the PE or E patient combined with PRESOther

According to the Diagnostic criteria of PRES, all the patients grouped into two groups.

PRES group

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age16 Years - 50 Years

Sexfemale

Healthy VolunteersNo

Age GroupsChild (0-17), Adult (18-64)

Sampling MethodNon-Probability Sample

Study Population

Pregnant Women diagnosed with PE or E.

You may qualify if:

Pregnant women were diagnosed of PE or E.

Sponsors & Collaborators

Dunjin Chen
Otherlead

Study Sites (1)

Department of Obstetrics and Gynecology, Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University

Guangzhou, 510150, China

MeSH Terms

Conditions

Posterior Leukoencephalopathy Syndrome

Interventions

Pressure

Condition Hierarchy (Ancestors)

Hypertensive EncephalopathyIntracranial HypertensionBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesLeukoencephalopathies

Intervention Hierarchy (Ancestors)

Mechanical PhenomenaPhysical Phenomena

Study Officials

Dunjin Chen
The Third Affiliated Hospital of Guangzhou Medical University
PRINCIPAL INVESTIGATOR

Enrollment

621 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE ONLY
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Director of obstetrics

Study Record Dates

First Submitted

June 16, 2022

First Posted

June 27, 2022

Study Start

July 1, 2022

Actual (reported)

Inflammatory Biomarkers for the Diagnosis of oPRES

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (2)

Secondary Outcomes (3)

Study Arms (2)

PRES group

NON-PRES group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (2)

Secondary Outcomes (3)

Study Arms (2)

PRES group

NON-PRES group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations