Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Burnout Syndrome

NCT05750160 | Completed DMC

• 1 other identifier: KET-1362/UN2.F1/ETIK/PPM.00.02
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Burnout Syndrome (BOS) can be defined as a state of stress both physically and psychically due to the burden and stressor of high work. The prevalence of BOS in health workers varies between 25-75% globally. Studies have shown that the presence of Burnout syndrome will meaningfully reduce the quality of services related to patient safety and cause immune system disorders that act as the body's defense against viral, bacterial, protozoal and fungal infections. Many strategies have been researched to help prevent and reduce the occurrence of Burnout syndrome, one of which is music therapy. The purpose of this study was to determine the effect of music therapy on the immune response in health workers with Burnout Syndrome. This study is a randomized clinical trial with a pre and post test control group design for health workers at Dr Kariadi General Hospital and Dr. Cipto Mangunkusumo General Hospital. Subjects will be provided with information prior to the study and asked to sign an informed consent sheet if they agree to be involved in the study. Subjects will be divided into control groups and treatment groups with matching age, gender and type of work. In the treatment group, music therapy will be given as much as 3 times a week for 4 weeks. Data were taken on both groups before and after the intervention. This study used the Maslach Burnout Inventory Human Service Survey (MBI-HSS) and blood laboratory examination to determine the value of the Neutrophyl Lymphocyte Ratio, Interleukin 6 and Interleukin 10 levels.

Conditions

Burnout Syndrome; Neutrophil-Lymphocyte Ratio; Interleukin-6; Interleukin-10

Outcome Measures

Primary Outcomes (4)

• Burnout syndrome

  Maslach Burnout Inventory Human Service Survey (MBI-HSS) score

  change from baseline score at 4 weeks

• Neutrophil Lymphocyte Ratio

  Measured with Fluorescence Flow Cytometry

  Change from baseline Neutrophil Lymphocyte Ratio at 4 weeks

• Interleukin 6

  Measured with Fluorescence Immunoassay

  Change from baseline Interleukin-6 level at 4 weeks

• Interleukin 10

  Measured with ELISA

  Change from baseline Interleukin-10 level at 4 weeks

Study Arms (2)

Control

NO INTERVENTION

Given education only

Intervention

EXPERIMENTAL

Given education and music therapy

Other: music therapy

Interventions

music therapy OTHER

Music therapy that have been made by Music Therapist after Focus Group discussion, given three times a week for 4 weeks

Intervention

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age 18 years - 60 years old
• Health workers in the wards and polyclinic of Dr. Cipto Mangunkusumo Hospital or Dr. Kariadi Hospital, including doctors in charge of patients, nurses, residents, and other supporting health workers
• Included in the Burnout syndrome criteria from the Maslach Burnout Inventory-Human Service Survey questionnaire

You may not qualify if:

• Refusing to follow the study
• Have a history of heart disease, kidney disease, diabetes, cancer, tuberkulosis, autoimmune, immunodeficiency
• Taking drugs that affect the central nervous system or immunosuppressants
• Have hearing disorder
• Have a psychiatric disorder
• Being pregnant
• Healthcare workers who don't like music

Sponsors & Collaborators

• Indonesia University: lead

Study Sites (1)

Cipto Mangunkusumo National Hospital

Jakarta, Indonesia

Location

MeSH Terms

Conditions

Burnout, Psychological

Interventions

Music Therapy

Condition Hierarchy (Ancestors)

Stress, Psychological; Behavioral Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Sensory Art Therapies; Complementary Therapies; Therapeutics; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Psychotherapy; Behavioral Disciplines and Activities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: January 15, 2023
• First Posted: March 1, 2023
• Study Start: February 13, 2023
• Primary Completion: February 18, 2023
• Study Completion: March 18, 2023
• Last Updated: June 5, 2023

Record last verified: 2023-06

Locations

ID (1)