NCT05431556

Brief Summary

The purpose of this study is to find out if it is practical to provide 2 interventions, VMB exercise classes and EUC (pre-recorded self-care videos), during the perioperative period (before and after surgery) to improve health-related outcomes and quality of life for people undergoing a pancreatectomy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
29

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2022

Typical duration for not_applicable

Geographic Reach
1 country

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 17, 2022

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

June 20, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 24, 2022

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 12, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 12, 2024

Completed
Last Updated

November 18, 2024

Status Verified

November 1, 2024

Enrollment Period

2.4 years

First QC Date

June 20, 2022

Last Update Submit

November 15, 2024

Conditions

Keywords

Exercises22-070

Outcome Measures

Primary Outcomes (1)

  • Feasibility of the Virtual Mind-Body Exercises program as measured by enrollment rate

    total number of patients invited, and the total number of study participants will be recorded

    1 year

Secondary Outcomes (1)

  • improving patient-reported outcomes (PROs)

    1 year

Study Arms (2)

Virtual mind-body group exercise classes (VMB)

EXPERIMENTAL

Will be provided with the schedule and links to the web-based mind-body exercises offered by MSK in real-time via the Zoom video conferencing platform. Each session is led by a licensed clinician (e.g., licensed dance therapist, certified yoga instructor, nurse specialist/physical trainer) with specific expertise in the oncology setting.

Other: Virtual mind-body group exercise classes

Enhanced usual care (EUC)

ACTIVE COMPARATOR

Pre-recorded self-care videos.

Other: Enhanced usual care

Interventions

Pre-operative period (baseline/intake day to day before surgery): mid- to high intensity classes focusing on aerobic physical activity, relaxation, and stress management (classes: Fitness for Everyone, Tai Chi, Mat Yoga, Dance Cardio, Meditation, Core Strength, Music Therapy) * Immediate post-operative period (post-operative hospitalization to 2 weeks after surgery): low- to mid-intensity classes focusing on relaxation, stress management and low-impact physical activity (classes: Chair Yoga, Dance Therapy, Meditation, Music Therapy) * Late post-operative period (3-12 weeks after surgery): mid- to high-intensity classes focusing on aerobic physical activity, relaxation, and stress management (classes: Fitness for Everyone, Tai Chi, Mat Yoga, Dance Cardio, Meditation, Core Strength, Music Therapy)

Virtual mind-body group exercise classes (VMB)

EUC arm will be referred to MSK's multimedia page on the Integrative Medicine website to access pre-recorded mind-body videos on their own time. These videos are 15-60 minutes in duration and consist of educational and self-care videos, including guided meditation and Tai Chi.

Enhanced usual care (EUC)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥ 18 years or older
  • Any pancreas disease (benign, pre-malignant, or malignant) and will be undergoing pancreatectomy
  • Has at least one week to participate in the study prior to the anticipated surgery date
  • Eastern Cooperative Oncology Group (ECOG) Performance status 0 or 1
  • English-speaking only

You may not qualify if:

  • Unable to give informed consent due to cognitive impairment or impaired decisionmaking capacity
  • Cognitive impairment precluding response to study assessments
  • Received neoadjuvant or any chemoradiation in the past 60 days
  • Unwilling to accept random assignment
  • Unwilling to commit to the 12-week study time period
  • Unlikely to be compliant because of social factors that prevent patients from attending classes or doing home practice (e.g., unreliable internet, no access to a computer)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

Memorial Sloan Kettering Basking Ridge (Consent Only)

Basking Ridge, New Jersey, 07920, United States

Location

Memorial Sloan Kettering Monmouth (Consent Only)

Middletown, New Jersey, 07748, United States

Location

Memorial Sloan Kettering Bergen (Consent Only)

Montvale, New Jersey, 07645, United States

Location

Memorial Sloan Kettering Suffolk- Commack (Consent Only)

Commack, New York, 11725, United States

Location

Memorial Sloan Kettering Westchester (Consent Only)

Harrison, New York, 10604, United States

Location

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, 10065, United States

Location

Memorial Sloan Kettering Nassau (Consent Only)

Uniondale, New York, 11553, United States

Location

Related Links

MeSH Terms

Conditions

Pancreatic DiseasesMotor Activity

Condition Hierarchy (Ancestors)

Digestive System DiseasesBehavior

Study Officials

  • Alice Wei, MD

    Memorial Sloan Kettering Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 20, 2022

First Posted

June 24, 2022

Study Start

June 17, 2022

Primary Completion

November 12, 2024

Study Completion

November 12, 2024

Last Updated

November 18, 2024

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will share

Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.

Locations