Status of Surgical Resection and Histologic Subtype as Predictors of Local Recurrence in Retroperitoneal Liposarcoma
1 other identifier
observational
60
1 country
1
Brief Summary
Soft tissue sarcomas are rare malignant tumors. Liposarcoma constitute the most frequent histological subtype of retroperitoneal sarcoma. The prognosis of soft tissue sarcomas depend on clinical and histologic characteristics. Objective: Evaluate variables that may be related to overall survival and local recurrence free survival in patients with retroperitoneal liposarcoma. Methods: retrospective analysis of medical records of 60 patients attended from 1997 to 2017, who underwent surgical resection of retroperitoneal liposarcoma.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Oct 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2018
CompletedFirst Submitted
Initial submission to the registry
April 9, 2019
CompletedFirst Posted
Study publicly available on registry
June 23, 2022
CompletedJune 23, 2022
June 1, 2022
1 year
April 9, 2019
June 18, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Overall survival rate
60 months
Local recurrence-free survival rate
60 months
Interventions
Retroperitoneal Liposarcoma resection
Eligibility Criteria
60 patients attended at the University of São Paulo Medical School Hospital (HC-FMUSP) and the Cancer Institute of the State of São Paulo (ICESP) from 1997 to 2017, who underwent surgical resection of the primary tumor at these institutions, as well as those referred after resection at other services.
You may qualify if:
- All patients who underwent surgical resection of retroperitoneal liposarcoma
You may not qualify if:
- Unresectable disease (upper mesenteric artery or vein involvement) or metastatic disease (sarcomatosis or distant disease)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
São Paulo, 05403000, Brazil
Related Publications (2)
Neuhaus SJ, Barry P, Clark MA, Hayes AJ, Fisher C, Thomas JM. Surgical management of primary and recurrent retroperitoneal liposarcoma. Br J Surg. 2005 Feb;92(2):246-52. doi: 10.1002/bjs.4802.
PMID: 15505870RESULTSinger S, Antonescu CR, Riedel E, Brennan MF. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Ann Surg. 2003 Sep;238(3):358-70; discussion 370-1. doi: 10.1097/01.sla.0000086542.11899.38.
PMID: 14501502RESULT
MeSH Terms
Conditions
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Full Professor of III General Surgery Division
Study Record Dates
First Submitted
April 9, 2019
First Posted
June 23, 2022
Study Start
October 1, 2017
Primary Completion
October 1, 2018
Study Completion
November 1, 2018
Last Updated
June 23, 2022
Record last verified: 2022-06
Data Sharing
- IPD Sharing
- Will not share