NCT05425511

Brief Summary

Work stress and psychosocial risks are a major public health problem. Health-care workers (HCW) are particularly at risk. Moreover, non-HCW staff of hospitals can also be at risk, with working environment described as the main risk factor. The University Hospital (CHU) of Clermont-Ferrand is one of the 3 CHUs in France with more than 10% absenteeism, and the first CHU for duration of sick leave. The political orientations favor an approach to improve the quality of life at work. Sophrology is a psychocorporal method used as a therapeutic technique or experienced as a philosophy of life. It is an exclusively verbal and non-tactile method. It combines a set of techniques that will act both on the body and on the mind through breathing exercises, muscle relaxation and mental imagery (or visualization). It allows to find a state of well-being and to activate all physical and psychological potential in order to acquire a better knowledge of oneself. NLP is a set of communication and self-transformation techniques that focuses on reactions rather than the origins of behaviors. NLP associated with sophrology proposes above all to mobilize the resources of the unconscious. Neurolinguistic programming (NLP) strategies are effective in the improvement in mental (anxiety and depression), physical, and social health, both in the general population, in individuals with social/psychological problems or in patients, both in hospital settings or outside hospital. Similary, sophrology also demonstrated some benefits on symptoms of patients. However, these approaches have never been provided in the workplace for the benefits of workers at risk of stress-related disorders. This protocol may permit improvements of stress-related outcomes. Putative short-term benefits: This protocol may incidentally detect cardiac disorders. Any abnormality discovered will not be covered by promotor's insurance (our exploratory study cannot lead to such event) and will be supported by health insurance. In general, the investigators aim to demonstrate the effectiveness of a workplace sophrology / NLP intervention for HCW at risk of stress-related disorders. Stress and well-being will be the target of the intervention, and will be measured both in a subjective (questionnaire) and objective (biomarkers).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
22mo left

Started Mar 2023

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress64%
Mar 2023Mar 2028

First Submitted

Initial submission to the registry

June 13, 2022

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 21, 2022

Completed
9 months until next milestone

Study Start

First participant enrolled

March 8, 2023

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2026

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2028

Expected
Last Updated

September 22, 2025

Status Verified

November 1, 2024

Enrollment Period

3 years

First QC Date

June 13, 2022

Last Update Submit

September 19, 2025

Conditions

Keywords

stressheart rate variabilitywell-being

Outcome Measures

Primary Outcomes (2)

  • heart rate variability (HRV) Description : Abrupt changes in HRV signals will be explored. Time Frame : During 34 hours in five different conditions

    HRV will be explored in time and frequency domains using Zephyr™ BioHarness™ BT.

    Once per session of sophrology (6 to 8 sessions) during the 2 months intervention

  • heart rate variability (HRV) Description : Abrupt changes in HRV signals will be explored. Time Frame : During 34 hours in five different conditions

    HRV will be explored in time and frequency domains using Zephyr™ BioHarness™ BT.

    Once per month during 6 months

Secondary Outcomes (39)

  • Skin conductance

    Once per session of sophrology (6 to 8 sessions) during the 2 months intervention

  • Skin conductance

    Once per month during 6 months

  • Demographics variables

    Once at inclusion

  • Clinical measurements (height)

    Once at inclusion

  • Clinical measurements (weight)

    Once at inclusion

  • +34 more secondary outcomes

Study Arms (2)

intervention group

EXPERIMENTAL

The intervention group will have a longitudinal follow-up of seven months in total (a control period of 1 month, then 6 to 8 sophrology sessions during two months, then a 4-month follow-up).

Behavioral: sophrology / neurolinguistic programming intervention

control group

ACTIVE COMPARATOR

The control group will have a differed intervention (longitudinal follow-up of seven months in total beginning by a control period without intervention of 3 months, then 6 to 8 sophrology sessions during two months, then a 2-month follow-up).

Behavioral: sophrology / neurolinguistic programming intervention

Interventions

2 sessions will be offered per week at 2 different time and will last 1 hour. They can take place in a seated or standing position, without physical contact. The sessions will consist of breathing exercises, visualization, dynamic relaxation and concentration exercises. The program is standardized: 1. Dialogue between the sophrologist and the participants. It is possible to specify the objective(s) of the session. The sophrologist can ask more specific questions to adapt the session. 2. Presentation of the conduct of the session (possible variations) and instructions promoting autonomy 3. Guided by the sophrologist, the goal is to help free yourself from tensions, to play down a situation that worries and finally to realize that we can deal with. Exercises are adapted to the difficulties encountered by the participants. 4. Time for free expression after the practice to promote the integration of the technique while giving elements to the sophrologist to guide the future sessions.

control groupintervention group

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • worker (HCW or NHCW) from a hospital,
  • age between 18-65 years,
  • with a stress greater than 50 on a visual analogue scale (VAS) of stress,
  • person able to give an informed consent to participate in research and
  • affiliated with a Social Security scheme

You may not qualify if:

  • Psychiatric, cardiovascular (heart failure, arrhythmia, etc.), hepatic (liver failure, etc.), renal (kidney failure, etc.), or endocrinological diseases (diabetes, etc.) judged by the investigator to be incompatible with the study because they may interfere with the measurements
  • Non-affiliated to a health insurance
  • Protected persons (minors, pregnant women, breastfeeding women, guardianship, curatorship, deprived of freedoms, safeguard of justice)
  • Refusal to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU clermont-ferrand

Clermont-Ferrand, France

RECRUITING

Related Publications (1)

  • Dutheil F, Parreira LM, Pereira B, Baldet M, Marson F, Chabaud C, Blot M, Baker JS, Zak M, Vallet G, Magnon V, Clinchamps M, Altun S. SOphrology Intervention to Improve WELL-Being in Hospital Staff (SO-WELL): Protocol for a Randomized Controlled Trial Study. Int J Environ Res Public Health. 2023 Jan 9;20(2):1185. doi: 10.3390/ijerph20021185.

Study Officials

  • Frédéric Dutheil

    University Hospital, Clermont-Ferrand

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: We will recruit workers from hospitals who will be randomized in two groups: * the intervention group will have a longitudinal follow-up of seven months in total (a control period of 1 month, then 6 to 8 sophrology sessions during two months, then a 4-month follow-up) * the control group will have a differed intervention (longitudinal follow-up of seven months in total beginning by a control period without intervention of 3 months, then 6 to 8 sophrology sessions during two months, then a 2-month follow-up).
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 13, 2022

First Posted

June 21, 2022

Study Start

March 8, 2023

Primary Completion

March 1, 2026

Study Completion (Estimated)

March 1, 2028

Last Updated

September 22, 2025

Record last verified: 2024-11

Locations