NCT05420376

Brief Summary

At least 80 patients who will undergo laparoscopic inguinal hernia repair surgery will be randomized into 2 groups. For the patients in the first group, the whole mesh will be laid on the area without being fixed. The patients in the second group will be given a mesh of the same size, but partially divided horizontally and wrapped around the spermatic cord. Demographic data of patients in both groups, quality of life data(Carolinas Comfort Scale) at postoperative 1st, 7th, 30th, 3rd and 6th months, postoperative pain (VAS values), clinical seroma rate, recurrence and other complications will be monitored. When the desired number of patients and follow-up period are reached, the data in the 2 groups will be compared.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 20, 2022

Completed
26 days until next milestone

First Posted

Study publicly available on registry

June 15, 2022

Completed
1 day until next milestone

Study Start

First participant enrolled

June 16, 2022

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 16, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 16, 2023

Completed
Last Updated

July 20, 2022

Status Verified

July 1, 2022

Enrollment Period

11 months

First QC Date

May 20, 2022

Last Update Submit

July 19, 2022

Conditions

Keywords

Laparoscopic Inguinal HerniaLaparoscopic HerniaWhole MeshSplit MeshTAPTEPPInguinal hernia

Outcome Measures

Primary Outcomes (2)

  • Carolinas Comfort Scale values

    Differences in postoperative pain and quality of life(Carolinas Comfort Scale at first month) in patients who use whole meshes and those who use split meshes.

    6 month

  • Recurrence rates

    Differences in recurrence rates in patients who use whole meshes and those who use split meshes.

    6 month

Secondary Outcomes (1)

  • Recurrence rates

    6 month

Study Arms (2)

Whole Mesh

ACTIVE COMPARATOR

For the patients in the first group, the whole patch will be laid on the area without being fixed.

Procedure: Split Mesh

Split Mesh

ACTIVE COMPARATOR

The patients in the second group will be given a patch of the same size, but partially divided horizontally and wrapped around the spermatic cord.

Procedure: Split Mesh

Interventions

Split MeshPROCEDURE

TEP repair of inguinal hernias using either split or whole mesh

Also known as: Whole mesh
Split MeshWhole Mesh

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Clinical or/and radiological diagnosed primary inguinal hernia
  • TEP or TAPP surgical methods

You may not qualify if:

  • Recurrent hernias
  • Patients with previous groin operations on same side
  • Pregnant women
  • Patients who did not accept to participate in the study
  • ASA score of 3 or higher,

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istanbul Training and Research Hospital

Istanbul, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Hernia, Inguinal

Condition Hierarchy (Ancestors)

Hernia, AbdominalHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Central Study Contacts

Erol Aydın, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
General Surgeon

Study Record Dates

First Submitted

May 20, 2022

First Posted

June 15, 2022

Study Start

June 16, 2022

Primary Completion

May 16, 2023

Study Completion

June 16, 2023

Last Updated

July 20, 2022

Record last verified: 2022-07

Locations