NCT05418231

Not Yet Recruiting

Observation of the Natural Course of Age-related Macular Deg...

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Source

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Other study identifiers

Sponsor study identifier

SXD20220609

Study Type

observational

Estimated enrollment

500

Locations

1 country

Sites

1

Timeline

Study Start

July 2022

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Primary Completion

January 2025

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Study Completion

July 2027

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Brief Summary

This research will study natural course of dry AMD in Chinese population, screen fundus imaging indicators for patients with Chinese dry AMD, describe the clinical features of Chinese patients with dry AMD, and obtain a biological sample library of dry AMD mainly in China.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: not yet recruiting
Estimated enrollment: 500 participants
Study completion date: July 2027
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

First Submitted
June 9, 2022
Actual (reported)
First Posted
June 14, 2022
Actual (reported)
Study Start
July 2022
Estimated (date passed)
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
January 2025
Estimated (date passed)
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
July 2027
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated: June 14, 2022
Status Verified: June 2022
Last Update Submitted: June 9, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

Visual acuity
A typical ETDRS chart that if frequently used for visual acuity testing
60 months

Secondary Outcomes (3)

Drusen density and shape
60 months
The rate of 5-year progression
60 months
GA growth rate
60 months

Eligibility Criteria

Age50 Years - 85 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Dry AMD patients in Shanghai General Hospital

You may qualify if:

yrs male or female AMD patients

Sponsors & Collaborators

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Otherlead

Study Sites (1)

Shanghai General Hospital, Shanghai Jiao Tong University

Shanghai, 200080, China

MeSH Terms

Conditions

Geographic Atrophy

Condition Hierarchy (Ancestors)

Macular DegenerationRetinal DegenerationRetinal DiseasesEye Diseases

Study Officials

Xiaodong Sun, PHD
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
PRINCIPAL INVESTIGATOR

Central Study Contacts

Junran Sun, M.D.

CONTACT

+8613661995933 emiliesun@sina.com

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Professor

Study Record Dates

First Submitted

June 9, 2022

First Posted

June 14, 2022

Study Start

July 2022

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Primary Completion

January 2025

Completed

NCT05536752

QA102 Phase II Study in Subjects With Dry AMD

Phase 2Completed

NCT03046407

Treatment of Dry Age Related Macular Degeneration Disease With Retinal Pigment Epithelium Derived From Human Embryonic Stem Cells

Phase 1/2Unknown

NCT04627428

Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)

Phase 1/2Recruiting

NCT02755428

Subretinal Transplantation of Retinal Pigment Epitheliums in Treatment of Age-related Macular Degeneration Diseases

Phase 1/2Unknown

NCT06018558

Study to Assess the Safety and Efficacy of OCU410 for Geographic Atrophy

Phase 1/2Active Not Recruiting

NCT06229665

Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITEIIIB)

Phase 2/3Unknown

Dry-AMD patients in either early, intermediate, or intermediate-to-late stage confirmed by fundus examinations.

You may not qualify if:

Any eye with disease that would interfere with the retinal examinations
Research eye with CNV or high myopia
Surgeries that may interfere with AMD evaluation
Long-term uses of medications that are associated with retinal or neural toxicities.
IOP more than 26 mmHg
Received cataract surgery in 3 months.
Other conditions: diseases that causes less than 5 years survival; any condition that causes high risk of drop-out, or low compliance, for instance cognition disorder; have been involved in other trial that interfere with the current visit plan; taking other angiogenesis Inhibitors drugs for treating cancer.
Other conditions not suitable for the current study

Contact the study team to confirm eligibility.

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Study Completion

July 2027

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated

June 14, 2022

Record last verified: 2022-06

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT05418231
Data provider: ClinicalTrials.gov
Source updated: 2022-06-14
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:21:10 UTC

Locations

CN(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations