Key Insights

Highlights

Success Rate

74% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

13.5%

5 terminated out of 37 trials

Success Rate

73.7%

-12.8% vs benchmark

Late-Stage Pipeline

5%

2 trials in Phase 3/4

Results Transparency

29%

4 of 14 completed with results

Key Signals

4 with results74% success

Data Visualizations

Phase Distribution

30Total
Not Applicable (8)
P 1 (9)
P 2 (11)
P 3 (2)

Trial Status

Completed14
Recruiting7
Terminated5
Active Not Recruiting4
Unknown3
Not Yet Recruiting2

Trial Success Rate

73.7%

Benchmark: 86.5%

Based on 14 completed trials

Clinical Trials (37)

Showing 20 of 20 trials
NCT03392324Not ApplicableActive Not RecruitingPrimary

PRIMA US-Feasibility Study in Atrophic Dry AMD

NCT03333954Not ApplicableCompletedPrimary

Feasibility Study of Compensation for Blindness With the PRIMA System in Patients With Dry Age Related Macular Degeneration

NCT06557460Phase 2RecruitingPrimary

A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)

NCT04339764Phase 1RecruitingPrimary

Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

NCT03846193Phase 1TerminatedPrimary

FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD

NCT04566445Phase 2TerminatedPrimary

HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

NCT04437368Phase 2TerminatedPrimary

EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

NCT04627428Phase 1RecruitingPrimary

Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)

NCT06536062Not ApplicableRecruitingPrimary

Age-related Macular Degeneration of Atrophic Type Treated With Umbilical Cord Blood Enriched With Platelet Plasma.

NCT05706896Not ApplicableRecruitingPrimary

Atrophic Age-related Macular Degeneration Treated With Intravitreal Injections of Umbilical Cord Blood Platelet-rich Plasma

NCT05447650Not ApplicableCompleted

Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT)

NCT05797896Active Not RecruitingPrimary

Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study

NCT02686658Phase 2Completed

Zimura in Participants With Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration

NCT03144999Phase 1CompletedPrimary

Treatment of Advanced Dry Age Related Macular Degeneration With AAVCAGsCD59

NCT00950638Phase 1CompletedPrimary

A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degeneration

NCT05536752Phase 2CompletedPrimary

QA102 Phase II Study in Subjects With Dry AMD

NCT03894020TerminatedPrimary

GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)

NCT06229665Phase 2Active Not RecruitingPrimary

Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITEIIIB)

NCT06351605RecruitingPrimary

A Registry Study to Assess Photobiomodulation in Dry Age-Related Macular Degeneration (EUROLIGHT) (EUROLIGHT)

NCT06165068Phase 3RecruitingPrimary

Effects of Antiplatelet and Antioxidant Agents on Drusen Progression: A Pilot, Prospective Cohort Study

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