Trials Sponsors Conditions Drugs Pricing

Conditions

Bariatric Surgery Candidate Digestive Organs--Cancer Parietal Region Trauma

Keywords

MitochondriaOxygraphyAdipose TissueBody Mass IndexDigestive surgery

Outcome Measures

Primary Outcomes (1)

Evaluation of mitochondrial respiration on adipose tissue by oxygraphy
Mitochondrial respiration measurements in oxydophosphorylated conditions. For each patient measurements using ADP and carbohydrate or lipid substrates of the respiratory chain complexes for both the subcutaneous and the visceral tissue.
day 1

Secondary Outcomes (3)

mitochondrial respiration values depending on patients BMI by oxygraphy
day 1
comparing mitochondrial respiration values depending on tissue location by oxygraphy
day 1

Study Arms (1)

All patients

EXPERIMENTAL

a sample of adipose tissue will be collected during the scheduled surgery

Procedure: adipose surgery

Interventions

adipose surgeryProcedure

A quantity of adipose tissue equivalent to 10-20 cubic centimeter will be removed subcutaneously and from the omentum during surgical procedures (oncological, bariatric)

All patients

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Patients undergoing oncological, bariatric, parietal surgery
Patients able to give an informed consent

Sponsors & Collaborators

University Hospital, Clermont-Ferrand
Otherlead

Study Sites (1)

CHU clermont-ferrand

Clermont-Ferrand, France

Related Publications (1)

Guerrier L, Bacoeur-Ouzillou O, Touron J, Mezher S, Cassagnes L, Vieille-Marchiset A, Chanon S, Pereira B, Pezet D, Pinel A, Gagniere J, Malpuech-Brugere C, Richard R. Mitochondrial respiration in white adipose tissue is dependent on body mass index and tissue location in patients undergoing oncological or parietal digestive surgery. FASEB J. 2025 Jan 31;39(2):e70350. doi: 10.1096/fj.202402243R.
PMID: 39856788RESULT

MeSH Terms

Conditions

Craniocerebral Trauma

Condition Hierarchy (Ancestors)

Trauma, Nervous SystemNervous System DiseasesWounds and Injuries

Study Officials

Ruddy RICHARD
University Hospital, Clermont-Ferrand
PRINCIPAL INVESTIGATOR

Enrollment

67 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: HEALTH SERVICES RESEARCH
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

May 17, 2022

First Posted

June 14, 2022

Study Start

April 14, 2021

Actual (reported)

Study Stopped

Mitochondrial Oxygraphy on Subcutaneous and Peri-visceral Adipose Tissue: Influence of Body Composition

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (1)

All patients

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (1)

All patients

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations