Stress Management and Resiliency Training Following Acute Myocardial Infarction

NCT05415735 | Completed

• 1 other identifier: 1787419
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this pilot study is to use total body PET/CT imaging to examine the relationships between stress, amygdala activation, and arterial wall inflammation in participants before and after participating in a multi-modal stress reduction program.

Conditions

Heart Attack; Cardiovascular Diseases

Outcome Measures

Primary Outcomes (1)

• Change in amygdala activation

  change in radiotracer uptake in the amygdala with FDG-PET imaging from before to after the SMART Program

  about 10 weeks

Study Arms (1)

SMART Program

EXPERIMENTAL

The Stress Management and Resiliency Training (SMART) Program is a multimodal mind-body and cognitive skills-based program that teaches participants a variety of different approaches for reducing their physiologic stress response. The program is delivered virtually (online) for 1.5 hours once a week for 8 weeks.

Behavioral: Stress Management and Resiliency Training Program

Interventions

Stress Management and Resiliency Training Program BEHAVIORAL

This is a multimodal mind-body program designed to teach participants a variety of different strategies to reduce their physiologic stress response.

SMART Program

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Concurrently enrolled in an observational study of patients who have had an acute myocardial infarction
• Score on PSS-10 of 14 or greater during screening
• Willing and able to access the internet to participate in the online SMART Program

You may not qualify if:

• Poorly controlled physical or mental health condition that would likely interfere with the ability to participate in SMART or ability to undergo PET scan
• Current daily practice of meditation of 10 minutes or more per day

Sponsors & Collaborators

• University of California, Davis: lead

Study Sites (1)

University of California Davis

Sacramento, California, 95817, United States

Location

MeSH Terms

Conditions

Myocardial Infarction; Cardiovascular Diseases

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Medicine

Study Record Dates

• First Submitted: June 8, 2022
• First Posted: June 13, 2022
• Study Start: May 11, 2022
• Primary Completion: December 8, 2022
• Study Completion: October 1, 2023
• Last Updated: May 21, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)