NCT05410028

Brief Summary

In this study, mass spectrometry was used to analyze immune inflammation-related protein complexes, post-translational modified glycopeptide omics and tumor-related metabolomics in serum, respectively, in order to find potential metabolic small molecule biomarkers or marker profiles that can be used for early diagnosis of cancer recurrence.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2022

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 3, 2022

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 4, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 8, 2022

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 3, 2024

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 3, 2026

Completed
Last Updated

June 8, 2022

Status Verified

March 1, 2022

Enrollment Period

2 years

First QC Date

June 4, 2022

Last Update Submit

June 4, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Immune Inflammation-Related Protein Complexes

    The change of immune inflammation-related protein complexes

    2 years

Interventions

No intervention in clinical treatment

Eligibility Criteria

Age20 Years - 70 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Before treatment, after surgery, during chemotherapy, and after chemotherapy, patients with confirmed ovarian epithelial cancer had different time cutoff points until clinically confirmed patients recurred.

You may qualify if:

  • Female
  • A diagnosed patient with epithelial ovarian cancer
  • Age ≤ 70

You may not qualify if:

  • Male
  • Suffering from other malignant tumors
  • Non-compliant patient
  • Age above 70

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

1 mL of serum

MeSH Terms

Conditions

Ovarian Neoplasms

Condition Hierarchy (Ancestors)

Endocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsOvarian DiseasesAdnexal DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Neoplasms, FemaleUrogenital NeoplasmsGenital DiseasesEndocrine System DiseasesGonadal Disorders

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 4, 2022

First Posted

June 8, 2022

Study Start

March 3, 2022

Primary Completion

March 3, 2024

Study Completion

March 3, 2026

Last Updated

June 8, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations