NCT05408806

Brief Summary

The aim of the research is to increase the active participation of children with Cerebral Palsy (CP) in therapy by integrating technological approaches into rehabilitation; To examine the effects of Nintendo Wii virtual reality games or hippotherapy simulator use on postural control, activity and participation in addition to Neurodevelopmental Therapy (NGT), which is frequently used in rehabilitation programs in CP, and to contribute to the relevant literature. H1/H1-0: In the rehabilitation of children with Cerebral Palsy, Nintendo Wii virtual reality games in addition to NGT has or has no effect on postural control, lower extremity selective motor control, spasticity, activity and participation levels. H2/H2-0: In the rehabilitation of children with Cerebral Palsy, Hippotherapy simulator in addition to NGT has or has no effect on postural control, lower extremity selective motor control, spasticity, activity and participation levels.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
34

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Mar 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2022

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

May 25, 2022

Completed
7 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 7, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2022

Completed
Last Updated

June 7, 2022

Status Verified

June 1, 2022

Enrollment Period

3 months

First QC Date

May 25, 2022

Last Update Submit

June 5, 2022

Conditions

Keywords

cerebral palsypostural controlrehabilitationvirtual reality gameshippotherapy simulator

Outcome Measures

Primary Outcomes (4)

  • Trunk Control Measurement Scale (TCMS)

    The Trunk Control Measurement Scale is a clinical tool to measure trunk control in children with cerebral palsy. The TCMS evaluates of static and dynamic sitting balance. TCMS consists of 15 questions in total. A higher score on this scale represents better performance, with a TCMS total score ranging from 0 to 58. We will use this scale at the beginning and end of our study (after 8 weeks) so that we can see the effectiveness of the treatment methods we will apply.

    Baseline and after 8 weeks

  • Selective Control Assessment of the Lower Extremity (SCALE)

    The Selective Control Assessment of the Lower Extremity (SCALE) is a clinical tool developed to quantify selective voluntary motor control (SVMC) in patients with cerebral palsy (CP). Hip, knee, ankle, subtalar, and toe joints are assessed bilaterally. We will use this scale at the beginning and end of our study (after 8 weeks) so that we can see the effectiveness of the treatment methods we will apply.

    Baseline and after 8 weeks

  • Modified Ashworth Scale (MAS)

    The Modified Ashworth Scale is the most universally accepted clinical tool used to measure the increase of muscle tone. Hip flexors, hip adductors, knee flexors and ankle plantar flexor muscles in the lower extremities of the cases are evaluated bilaterally. We will use this scale at the beginning and end of our study (after 8 weeks) so that we can see the effectiveness of the treatment methods we will apply.

    Baseline and after 8 weeks

  • BeCure Balance Assessment System

    The developed system evaluates the person's static standing balance, body center of gravity, load distributions in each foot, postural sway and proprioception. Evaluations made on the Nintendo Wii balance platform can be made as one foot-two feet, eyes open-closed, with or without images. We will use this scale at the beginning and end of our study (after 8 weeks) so that we can see the effectiveness of the treatment methods we will apply.

    Baseline and after 8 weeks

Secondary Outcomes (2)

  • Pediatric Evaluation of Disability Inventory (PEDI)

    Baseline and after 8 weeks

  • Pediatric Quality of Life Inventory™ (PedsQL) 3.0 CP Module

    Baseline and after 8 weeks

Study Arms (2)

Virtual Reality Games Group with Nintendo Wii Balance Platform

In addition to neurodevelopmental treatment, the cases are treated with virtual reality (VR) games on nintendo wii balance board for 8 weeks, 2 sessions a week. The VR games are performed twice in the first four weeks at the beginner level. During the following four weeks, advanced levels of the same games are selected and virtual reality therapy is performed with 2 repetitions.

Other: Exercise Interventions

Hippotherapy Simulator Group

In addition to neurodevelopmental treatment, the cases are treated on a hippotherapy simulator for 8 weeks, 2 sessions a week. In the first 4 weeks, the warm-up and 1 speed intensities of the hippotherapy simulator are applied. During the next 4 weeks, cases are treated warm-up, 1, 2, 3, speed intensities, respectively.

Other: Exercise Interventions

Interventions

Rehabilitation methods and exercise practices to improve postural control in children with cerebral palsy. In addition to neurodevelopmental treatment, one group is treated with virtual reality games and the other group is treated with a hippotherapy simulator.

Hippotherapy Simulator GroupVirtual Reality Games Group with Nintendo Wii Balance Platform

Eligibility Criteria

Age5 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

Children between the ages of 5 and 18 who have been diagnosed with spastic cerebral palsy constitute the population of the study.

You may qualify if:

  • Having been diagnosed with spastic type CP,
  • Being between the ages of 5-18,
  • In Gross Motor Function Classification System (KMFSS); Taking place at I-II-III level,
  • The family and the child agreed to participate in the study after reading the informed consent form.

You may not qualify if:

  • Botulinum Toxin (BOTOX) injection to the lower extremity in the last 6 months,
  • Having a diagnosis of epilepsy
  • Having been diagnosed with mental retardation,
  • Receiving additional treatment other than neurodevelopmental treatment,
  • Having a vision and/or hearing problem that may affect participation in treatment methods.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istanbul University-Cerrahpasa

Istanbul, 34500, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Yonca Zenginler Yazgan, Asst.Prof.

    Istanbul University - Cerrahpasa

    STUDY DIRECTOR

Central Study Contacts

Irem N Sener, BsC

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Asst. Prof.

Study Record Dates

First Submitted

May 25, 2022

First Posted

June 7, 2022

Study Start

March 1, 2022

Primary Completion

June 1, 2022

Study Completion

August 1, 2022

Last Updated

June 7, 2022

Record last verified: 2022-06

Data Sharing

IPD Sharing
Will not share

Locations