NCT05403008

Brief Summary

This randomized clinical study aims to evaluate the clinical performance and occlusal wear resistance of nano-zirconia reinforced glass ionomer restorations in comparison to Nano-hybrid resin composite in proximal cavities.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2022

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 2, 2022

Completed
4 months until next milestone

Study Start

First participant enrolled

June 1, 2022

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2022

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 2, 2022

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2023

Completed
Last Updated

June 2, 2022

Status Verified

May 1, 2022

Enrollment Period

Same day

First QC Date

February 2, 2022

Last Update Submit

May 29, 2022

Conditions

Outcome Measures

Primary Outcomes (7)

  • Clinical performance

    Postoperative Hypersensitivity Secondary caries

    Change from the baseline at 6 months and at 12 months.

  • Clinical performance

    Secondary caries and measured by Modified United States Public Health Service Criteria (USPHS)

    Change from the baseline at 6 months and at 12 months.

  • Clinical performance

    Gross fracture and measured by Modified United States Public Health Service Criteria (USPHS)

    Change from the baseline at 6 months and at 12 months.

  • Clinical performance

    Color match and measured by Modified United States Public Health Service Criteria (USPHS)

    Change from the baseline at 6 months and at 12 months.

  • Clinical performance

    Cavo-surface marginal discoloration and measured by Modified United States Public Health Service Criteria (USPHS)

    Change from the baseline at 6 months and at 12 months.

  • Clinical performance

    Marginal integrity and measured by Modified United States Public Health Service Criteria (USPHS)

    Change from the baseline at 6 months and at 12 months.

  • Clinical performance

    Proximal contact and measured by Modified United States Public Health Service Criteria (USPHS)

    Change from the baseline at 6 months and at 12 months.

Secondary Outcomes (1)

  • Wear resistance evaluation

    Change from the baseline at 6 months and at 12 months.

Study Arms (2)

Zirconomer improved

OTHER

a nano zirconia reinforced glass ionomer, which has improved the mechanical, esthetic and handling properties than its previous successor.

Other: Zirconomer improved

Nano hybird resin composite

ACTIVE COMPARATOR

Resin composite (RC) is the gold standard esthetic restoration in proximal cavities due to their high aesthetic properties, increased mechanical durability and enhanced adhesion to tooth structure.

Other: Zirconomer improved

Interventions

Zirconomer improved, is a nano zirconia reinforced glass ionomer, which has improved the mechanical, esthetic and handling properties than its previous successor.

Nano hybird resin compositeZirconomer improved

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age group 18-55
  • Presence of occluding tooth.
  • Good oral hygiene

You may not qualify if:

  • Poor periodontal status
  • Adverse medical history.
  • Potential behavioral problems

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Dental Caries

Condition Hierarchy (Ancestors)

Tooth DemineralizationTooth DiseasesStomatognathic Diseases

Study Officials

  • Ahmed El-Hoshy, Professor

    Cairo University

    STUDY DIRECTOR

Central Study Contacts

weaam mohamed ammar, master

CONTACT

Rawda Hesham Abd ElAziz, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
Assessors and statistician
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Master degree student, Conservative Dentistry Department, Faculty of Dentistry, Cairo University.

Study Record Dates

First Submitted

February 2, 2022

First Posted

June 2, 2022

Study Start

June 1, 2022

Primary Completion

June 1, 2022

Study Completion

February 1, 2023

Last Updated

June 2, 2022

Record last verified: 2022-05