NCT04329858

Brief Summary

natural teeth will be filled with the 3 different material then the dentin sample will be collected ,bacterial culture and elementary analysis will be done

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2021

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 17, 2018

Completed
1.7 years until next milestone

First Posted

Study publicly available on registry

April 1, 2020

Completed
1.3 years until next milestone

Study Start

First participant enrolled

July 15, 2021

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 15, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 15, 2021

Completed
Last Updated

April 1, 2020

Status Verified

March 1, 2020

Enrollment Period

Same day

First QC Date

July 17, 2018

Last Update Submit

March 30, 2020

Conditions

Dental Caries

Outcome Measures

Primary Outcomes (2)

  • bacterial count

    streptococcus mutant count by culture of dentin sample excavated from the tooth after restoration removal

    3months

  • elementary analysis of dentin

    elementary analysis of dentin component excavated from the cavity after restoration removal to detect the change in tooth mineral

    3months

Study Arms (3)

conventional glass ionomer

ACTIVE COMPARATOR
Procedure: conventional glass ionomer

zinc modified glass ionomer

EXPERIMENTAL
Procedure: zinc modified

silver modified glass ionomer

EXPERIMENTAL
Procedure: silver modified glass ionomer

Interventions

silver modified glass ionomerPROCEDURE

occlusal cavity filled with silver modified

silver modified glass ionomer
zinc modifiedPROCEDURE

occlusal cavity filled with zinc modified

zinc modified glass ionomer
conventional glass ionomerPROCEDURE

occlusal cavity filled with conventional glass ionomer

conventional glass ionomer

Eligibility Criteria

Age10 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • patient need teeth extraction for orthodontic treatment

You may not qualify if:

  • carious teeth deciduous teeth

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Dental Caries

Condition Hierarchy (Ancestors)

Tooth DemineralizationTooth DiseasesStomatognathic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
assistant lecturer

Study Record Dates

First Submitted

July 17, 2018

First Posted

April 1, 2020

Study Start

July 15, 2021

Primary Completion

July 15, 2021

Study Completion

July 15, 2021

Last Updated

April 1, 2020

Record last verified: 2020-03