NCT05400252

Brief Summary

Recent Veterans of the Afghanistan and Iraq conflicts are presenting in VA care with high rates of posttraumatic stress disorder (PTSD), depression, anxiety, and substance use disorders. Difficulties with social relationships and community reintegration are common functional impairments with these disorders. VA is transforming to a Whole Health, patient-centered system of care that will address these issues as part of health care. In a previous study, Omnis Salutis (OS) was developed with Veteran and clinician input. OS is a three-session intervention in which Veterans learn about Whole Health and practice communicating their health mission to providers and social supports. OS was shown feasible to deliver, acceptable to Veterans, and preliminarily effective at improving physical, mental, and social functioning. This study will use a large, multisite randomized controlled trial to test the impact of OS on Veterans' social and physical functioning and Veteran engagement in mental health care. Results will support broad delivery of OS throughout the VA.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
238

participants targeted

Target at P75+ for not_applicable

Timeline
7mo left

Started Feb 2023

Longer than P75 for not_applicable

Geographic Reach
1 country

3 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress86%
Feb 2023Oct 2026

First Submitted

Initial submission to the registry

May 26, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 1, 2022

Completed
8 months until next milestone

Study Start

First participant enrolled

February 1, 2023

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Expected
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2026

Last Updated

January 9, 2026

Status Verified

January 1, 2026

Enrollment Period

3.2 years

First QC Date

May 26, 2022

Last Update Submit

January 7, 2026

Conditions

Keywords

Patient ParticipationPsychosocial FunctioningCommunicationPatient SatisfactionPatient Preference

Outcome Measures

Primary Outcomes (2)

  • Veterans RAND 36-Item Health Survey - Physical Component Summary

    overall physical functioning; Item response scales differ but are scored on a 3-, 5-, or 6-point scale (possible range 0-64). Item responses are summed with higher scores indicating better functioning.

    6 months

  • Veterans RAND 36-Item Health Survey - Social Functioning Scale

    overall social functioning in life; Item response are scored on a 5-point scale (possible range 0-4) with higher scores indicating better functioning.

    6 months

Secondary Outcomes (2)

  • Altarum Consumer Engagement - Commitment and Navigation subscales

    12 months

  • VA service use

    12 months

Study Arms (2)

Omnis Salutis

EXPERIMENTAL

Omnis Salutis is a Veteran-targeted, Whole Health program for mental health care settings and teaches Veterans the skills to identify and communicate their Whole Health goals to providers and social supports

Behavioral: Omnis Salutis

Health and Wellness

ACTIVE COMPARATOR

Health \& Wellness is an educational wellness intervention

Behavioral: Health and Wellness

Interventions

Omnis SalutisBEHAVIORAL

Omnis Salutis is a Veteran-targeted, Whole Health program for mental health care settings and teaches Veterans the skills to identify and communicate their Whole Health goals to providers and social supports

Omnis Salutis

Health \& Wellness is an educational wellness intervention

Health and Wellness

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Per medical record review:
  • military service since 2001
  • Veteran accessed MHC service at designated study site for the first time in the last 6 months OR the first time in the last 6 months after at least a one year gap in mental health care
  • have a current diagnosis of:
  • PTSD (309.81)
  • major depressive disorder (296.20-296.23, 296.30-296.33)
  • social anxiety disorder (300.23)
  • panic disorder (300.01)
  • generalized anxiety disorder (300.02)
  • other specified or unspecified anxiety disorder (300.09, 300.00)
  • substance use disorders (303.90, 304.00, 304.10, 304.30)

You may not qualify if:

  • Per medical record review, current diagnosis of a psychotic disorder meeting criteria established by the VA Serious Mental Illness Treatment, Research, and Evaluation Center (SMITREC):
  • schizophrenic disorders (295.0-295.9)
  • affective psychoses (296.0-296.1, 296.4-296.8)
  • major depression with psychotic features (296.24, 296.34)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Rocky Mountain Regional VA Medical Center, Aurora, CO

Aurora, Colorado, 80045-7211, United States

RECRUITING

Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD

Baltimore, Maryland, 21201, United States

RECRUITING

Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD

Baltimore, Maryland, 21201, United States

RECRUITING

MeSH Terms

Conditions

Stress Disorders, Post-TraumaticDepressive DisorderAnxiety DisordersSubstance-Related DisordersPatient ParticipationCommunicationPatient SatisfactionPatient Preference

Interventions

Health

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental DisordersMood DisordersChemically-Induced DisordersPatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Intervention Hierarchy (Ancestors)

Population Characteristics

Study Officials

  • Diana P Whitham, PhD MPH RD

    Rocky Mountain Regional VA Medical Center, Aurora, CO

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Alicia Lucksted, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcomes assessors will be blind to participant intervention assignment.
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 26, 2022

First Posted

June 1, 2022

Study Start

February 1, 2023

Primary Completion (Estimated)

May 1, 2026

Study Completion (Estimated)

October 31, 2026

Last Updated

January 9, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations