NCT05380908

Brief Summary

This study is a retrospective study, screening patients with systemic PET / CT scan in our department, enrolling the ones who meet the criteria, collect their information and resting state brain PET images.Then make the brain metabolic network analysis and statistical analysis to explore the PET brain metabolic network of non-small cell lung cancer patients and the effect of chemotherapy drugs on brain metabolic network in patients with advanced lung cancer.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2017

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2021

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

May 13, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 19, 2022

Completed
Last Updated

May 19, 2022

Status Verified

May 1, 2022

Enrollment Period

3.7 years

First QC Date

May 13, 2022

Last Update Submit

May 18, 2022

Conditions

Advanced Non-small-cell Lung Cancer

Outcome Measures

Primary Outcomes (1)

  • Death

    1-5 years

Study Arms (3)

Patients with untreated non-small cell lung cancer

Other: None of any intervention

Patients with non-small cell lung cancer after chemotherapy

Normal controls

Other: None of any intervention

Interventions

None of any interventionOTHER

The patients did not have any intervention.

Normal controlsPatients with untreated non-small cell lung cancer

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with pathological confirmed non-small cell lung cancer

You may qualify if:

  • Patients with advanced non-small cell lung cancer without any treatment and pathological confirmed non-small cell lung cancer.

You may not qualify if:

  • Brain tumors (primary or metastasis), previous surgery, radiotherapy, chemotherapy, stroke, head trauma, psychiatric history (insomnia, depression, mania, schizophrenia and other psychiatric disorders), or history of drug dependence (e. g. sedatives, sleeping pills or sedatives)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

PET/CT

Zhuhai, Guangdong, 519000, China

Location

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 13, 2022

First Posted

May 19, 2022

Study Start

June 1, 2017

Primary Completion

February 28, 2021

Study Completion

February 28, 2021

Last Updated

May 19, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will not share

Locations

CN(1)