NCT04455984

Brief Summary

This study retrospectively evaluates clinical parameters and outcome of patients with advanced stage non-small cell lung cancer treated with neoadjuvant therapy followed by curative-intent surgery at the Divison of Thoracic Surgery at the Medical University of Vienna

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
190

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2017

Completed
3.2 years until next milestone

First Submitted

Initial submission to the registry

June 29, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 2, 2020

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2020

Completed
Last Updated

July 7, 2020

Status Verified

July 1, 2020

Enrollment Period

3.3 years

First QC Date

June 29, 2020

Last Update Submit

July 2, 2020

Conditions

Advanced Non-small-cell Lung Cancer

Outcome Measures

Primary Outcomes (1)

  • Overall survival

    * Overall survival of stage III NSCLC in resectable patients undergoing induction treatment and curative intent surgery * Overall survival of stage III NSCLC in resectable patients undergoing induction treatment and curative intent surgery * Overall survival of stage III NSCLC in resectable patients undergoing induction treatment and curative intent surgery Overall survival of stage III NSCLC in resectable patients undergoing induction treatment and curative intent surgery

    18 years

Study Arms (2)

Neoadjuvant chemoradiotherapy

Patients with advanced NSCLC treated with neoadjuvant platinum-based chemoradiotherapy followed by curative-intent surgery

Other: Date collection

Neoadjuvant chemotherapy

Patients with advanced NSCLC treated with neoadjuvant platinum-based chemotherapy followed by curative-intent surgery

Other: Date collection

Interventions

Date collectionOTHER

Retrospective data analysis

Neoadjuvant chemoradiotherapyNeoadjuvant chemotherapy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients with non-small-cell lung cancer, who received an induction chemo- or chemoradiotherapy followed by surgery in a curative intention at the Devision of Thoracic Surgery, Medical University.

You may qualify if:

  • Patients with advanced NSCLC and multimodality treatment including curative-intent resection

You may not qualify if:

  • Patients with early stage NSCLC
  • Patients with advanced NSCLC without multimodality treatment
  • Patients without curative resection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical University of Vienna

Vienna, Austria

RECRUITING

Central Study Contacts

Katharina Sinn, MD

CONTACT

004314040056440katharina.sinn@meduniwien.ac.at

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

June 29, 2020

First Posted

July 2, 2020

Study Start

May 1, 2017

Primary Completion

August 1, 2020

Study Completion

August 1, 2020

Last Updated

July 7, 2020

Record last verified: 2020-07

Data Sharing

IPD Sharing
Will not share

Locations

AU(1)