Effect of a Third COVID-19 Booster Among Health Care Workers
1 other identifier
observational
3,167
1 country
1
Brief Summary
A new wave of COVID-19 infections, mainly caused by the Omicron/ Delta variant, has been sweeping the globe since the start of 2022. In response, the administration of a third dose of COVID-19 vaccine was considered to address potential waning immunity over time and reduced effectiveness against the Omicron/ Delta variant. The pandemic also resulted in many infections among health care workers (HCWs) and their households. In this study, a retrospective analysis would perform on risk of COVID-19 infection and their outcome in relation to their COVID-19 vaccination history by using the data repository from one of the Hong Kong private hospitals. HCWs were required to submit a standardized online self-declaration form for report of 1) demographic of the HCWs, 2) symptoms related history and 3) COVID-19 exposure history once they were COVID-19 confirmed by rapid antigen test against COVID-19 and/or polymerase chain reaction (PCR) test for COVID-19. Subsequent follow up such as contact tracing, COVID-19 PCR testing results of these HCWs and status of return to work were captured by the infection control team in a systematic manner.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2022
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 12, 2022
CompletedFirst Posted
Study publicly available on registry
May 13, 2022
CompletedStudy Start
First participant enrolled
May 16, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2022
CompletedFebruary 28, 2024
February 1, 2024
8 months
May 12, 2022
February 26, 2024
Conditions
Outcome Measures
Primary Outcomes (2)
COVID-19 Infection
Number of participants with COVID-19 infected
During 1 February - 31 March 2022
Number of days return to work after COVID-19 infection
Number of days return to work after COVID-19 infection
During 1 February - 31 March 2022
Study Arms (2)
Health care workers without third COVID-19 booster
Health care workers received less than 3 doses of COVID-19 vaccine
HCWs with third COVID-19 booster
Health care workers received at least 3 doses of COVID-19 vaccine
Interventions
Eligibility Criteria
All full time staff members of the private hospital
You may qualify if:
- All full time staff members of the private hospital
You may not qualify if:
- History of COVID-19 before 2022
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hong Kong Sanatorium & Hospital
Hong Kong, Hong Kong
MeSH Terms
Interventions
Study Officials
- PRINCIPAL INVESTIGATOR
Jonpaul Sze Tsing Zee, MBChB
Hong Kong Sanatorium & Hospital
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- INDUSTRY
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Specialist in Infectious Disease
Study Record Dates
First Submitted
May 12, 2022
First Posted
May 13, 2022
Study Start
May 16, 2022
Primary Completion
December 31, 2022
Study Completion
December 31, 2022
Last Updated
February 28, 2024
Record last verified: 2024-02
Data Sharing
- IPD Sharing
- Will not share