NCT04801524

Brief Summary

This study investigates whether and which type of text-based reminders affect the take-up of the COVID-19 vaccine.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
250,000

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 7, 2021

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 15, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 17, 2021

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2021

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2022

Completed
Last Updated

September 13, 2022

Status Verified

September 1, 2022

Enrollment Period

11 months

First QC Date

March 15, 2021

Last Update Submit

September 11, 2022

Conditions

Covid19, Vaccines

Keywords

COVID19VaccinesText-messagesPatient OutreachBehavioral Science

Outcome Measures

Primary Outcomes (1)

  • First COVID-19 Vaccine Appointment Scheduled at UCLA Health

    Whether patients schedule their vaccination appointment at UCLA Health within 6 days of receiving the second text message (including the day of text message). Specifically, if t=the date of the second text message (for the holdout arm, this refers to the date they would have received the text message had they not been assigned to the holdout arm), we will track vaccination appointments made by the end of t+5. While most people just make one appointment, a small percentage update their appointment time. We will have access to the latest few first-dose appointments people schedule by the time of data extraction.

    6 days

Secondary Outcomes (4)

  • First COVID-19 Vaccine obtained at UCLA Health

    1 months from text message

  • Time of obtaining the first COVID-19 vaccine at UCLA Health

    1 months from text message

  • First COVID-19 Vaccine obtained at UCLA Health or any organization reporting to CAIR

    2 months from text message

  • Time of obtaining the first COVID-19 at UCLA Health or another location reporting to CAIR

    2 months from text message

Study Arms (7)

Holdout Arm

NO INTERVENTION

In the Holdout arm: patients will not receive a second text message about COVID-vaccine.

Self-benefit sub-arm

EXPERIMENTAL

In the Self-benefit sub-arm, participants will be reminded that the vaccine helps protect themselves from COVID.

Behavioral: Self-benefit

Prosocial-benefit sub-arm

EXPERIMENTAL

In the Prosocial-benefit sub-arm, participants will be reminded that the vaccine helps protect their family, friends, and community from COVID.

Behavioral: Prosocial-benefit

Early-access and self-benefit sub-arm

EXPERIMENTAL

In the Early access + self-benefit sub-arm, participants will be reminded that they have early access to COVID-19 vaccine and should take the opportunity to protect themselves from COVID.

Behavioral: Self-benefitBehavioral: Early access

Early-access and prosocial-benefit sub-arm

EXPERIMENTAL

In the Early access + prosocial-benefit sub-arm, participants will be reminded that they have early access to COVID-19 vaccine and should take the opportunity to protect their family, friends, community from COVID.

Behavioral: Prosocial-benefitBehavioral: Early access

Fresh start and self-benefit sub-arm

EXPERIMENTAL

In the Fresh start + self-benefit sub-arm, participants will be reminded that the vaccine offers the promise of a fresh start and they should take the opportunity to protect themselves from COVID and chart a new path forward.

Behavioral: Self-benefitBehavioral: Fresh start

Fresh start and prosocial-benefit sub-arm

EXPERIMENTAL

In the Early access + prosocial-benefit sub-arm, participants will be reminded that the vaccine offers the promise of a fresh start and they should take the opportunity to protect their family, friends, community from COVID and help our nation chart a new path forward.

Behavioral: Prosocial-benefitBehavioral: Fresh start

Interventions

Self-benefitBEHAVIORAL

Participants will be reminded that the vaccine helps protect themselves from COVID.

Early-access and self-benefit sub-armFresh start and self-benefit sub-armSelf-benefit sub-arm
Prosocial-benefitBEHAVIORAL

Participants will be reminded that the vaccine helps protect their family, friends, and community from COVID

Early-access and prosocial-benefit sub-armFresh start and prosocial-benefit sub-armProsocial-benefit sub-arm
Early accessBEHAVIORAL

Participants will be reminded that they have early access to COVID-19 vaccine.

Early-access and prosocial-benefit sub-armEarly-access and self-benefit sub-arm
Fresh startBEHAVIORAL

Participants will be reminded that the vaccine offers the promise of a fresh start and chart a new path forward.

Fresh start and prosocial-benefit sub-armFresh start and self-benefit sub-arm

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All patients who satisfy the following criteria will be eligible to be included in our study:
  • They have a mobile phone number or SMS capable phone number in UCLA Health's database
  • They are eligible for receiving the COVID-19 vaccine at UCLA Health
  • They have not already scheduled an appointment the day before the scheduled time of the text message
  • They are at or above 18 years old

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UCLA Health Department of Medicine, Quality Office

Westwood, Los Angeles, California, 90095, United States

Location

Related Publications (3)

  • Brewer NT, Chapman GB, Rothman AJ, Leask J, Kempe A. Increasing Vaccination: Putting Psychological Science Into Action. Psychol Sci Public Interest. 2017 Dec;18(3):149-207. doi: 10.1177/1529100618760521.

    PMID: 29611455BACKGROUND

  • Volpp KG, Loewenstein G, Buttenheim AM. Behaviorally Informed Strategies for a National COVID-19 Vaccine Promotion Program. JAMA. 2021 Jan 12;325(2):125-126. doi: 10.1001/jama.2020.24036. No abstract available.

    PMID: 33315079BACKGROUND

  • Dai, H., Milkman, K. L., & Riis, J. (2014). The fresh start effect: Temporal landmarks motivate aspirational behavior. Management Science, 60(10), 2563-2582.

    BACKGROUND

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, CARE PROVIDER
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Medical Director of Quality, Dept of Medicine

Study Record Dates

First Submitted

March 15, 2021

First Posted

March 17, 2021

Study Start

February 7, 2021

Primary Completion

December 31, 2021

Study Completion

January 1, 2022

Last Updated

September 13, 2022

Record last verified: 2022-09

Data Sharing

IPD Sharing
Will not share

Locations

US(1)