Low Versus Moderate-intensity Aerobic Training in Post-discharge COVID-19 Subjects

NCT05373407 | Completed

• 1 other identifier: 00000
• Study Type: interventional
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

The main purpose of this study is to compare the impact of low versus moderate-intensity aerobic training in post-COVID 19 older subjects. On exercise adherence and changes in physical fitness, psychological status, and quality of life after a 10-week intervention.

Conditions

COVID-19; Aerobic Exercises; Elderly

Outcome Measures

Primary Outcomes (2)

• Distance walked in the 6-min walk test (6 MWT)

  The 6-min walk test (6 MWT) measures the distance that a patient can quickly walk on a flat, hard surface in a period of 6 minutes (the 6MWD). (ATS Statement: Guidelines for the Six-Minute Walk Test, Am J Respir Crit Care Med, 2002)

  8 weeks

• Post-Covid Functional Scale (PCFS)

  This scale measures the functional state and Independence of patients after COVID-19 infection. The scale includes two items scored from 0-4 and 0-5. A high value indicates more restrictions in function and independence during daily life.

  8 weeks

Secondary Outcomes (3)

• Number of repetitions performed in a 1-min Sit-to-Stand (STS) test

  8 weeks

• 2. Anxiety and Depression evaluated by the HAMLITON ScAnxiety and Depressionale (HADS)

  8 weeks

• Quality of life SF-36

  8 weeks

Study Arms (2)

moderate intensity aerobic training

EXPERIMENTAL

The exercises were conducted at a heart rate of 50-70% of maximum heart rate for 30 minutes. Exercises were included strengthening muscles groups (shoulder flexors, extensors, abductor's muscles, hip flexors, extensor muscles, knee flexors, extensor muscles, abdominal muscles, and back muscles).

Other: aerobic exercise

low intensity aerobic training

EXPERIMENTAL

Exercises were performed at 40-50% of the maximum heart rate Starting by 15 minutes of Warm-up time included static stretching of upper and lower body muscles. After that, participants performed 30 minutes of low-intensity aerobic training exercises, which included 20 minutes on the treadmill, followed by 10 minutes of cooling down. A set of 5-10 exercises was performed by each muscle group, three sets per exercise were performed, and 10-15 repetitions per series were performed 4 days per week

Other: aerobic exercise

Interventions

aerobic exercise OTHER

participants will perform different dosage of the same intervention, one group will perform moderate intensity and the other will perform low intensity aerobic training

low intensity aerobic training; moderate intensity aerobic training

Eligibility Criteria

• Age: 60 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age range of 60 - 80 years with
• diagnosis of post-COVID-19

You may not qualify if:

• History of lower limb surgeries, fractures
• Cardiac problems
• Respiratory problems
• Neurological problems
• Systemic problems and any other contraindications for aerobic training

Sponsors & Collaborators

• University of Hail: lead

Study Sites (1)

Hail University Poly Clinic

Hail, 2442, Saudi Arabia

Location

MeSH Terms

Conditions

COVID-19

Interventions

Exercise

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: May 12, 2022
• First Posted: May 13, 2022
• Study Start: August 15, 2022
• Primary Completion: October 30, 2022
• Study Completion: December 1, 2022
• Last Updated: December 14, 2022

Record last verified: 2022-12

Data Sharing

• IPD Sharing: Will not share

Locations

SA (1)