NCT05371691

Brief Summary

A randomized clinical trial is set out to compare the effectiveness of two types of functional appliances in the correction of a Class II malocclusion. (Class II malocclusions are where upper front teeth bite significantly further forward in relation to lower front teeth).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2021

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 10, 2021

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

April 26, 2022

Completed
16 days until next milestone

First Posted

Study publicly available on registry

May 12, 2022

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 10, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 10, 2024

Completed
Last Updated

November 28, 2023

Status Verified

November 1, 2023

Enrollment Period

2.8 years

First QC Date

April 26, 2022

Last Update Submit

November 27, 2023

Conditions

Keywords

Myofunctional applianceMyobrace.Twin-blockCl II div I malocclusion

Outcome Measures

Primary Outcomes (1)

  • Dentoskeletal changes

    Evaluation of dentoskeletal and soft tissue changes following the treatment of growing children with myobrace and twin block appliances. Using cephalometric analysis to measure the angles including dental angles such as inter-incisal angle, in addition to skeletal angles such as SNA,SNB and ANB angles.

    T1 at the start of treatment and T2 at the end of treatment around 9 months

Secondary Outcomes (2)

  • Soft tissue changes

    T1 at the start of treatment and T2 at the end of treatment around 9 months

  • Patient satisfaction

    At the end of treatment (around 9 months)

Study Arms (2)

Myobrace group

EXPERIMENTAL

Myobrace appliance will be used for children who have Cl.II div.a malocclusion

Device: Myofunctional appliance

Twin-block group

EXPERIMENTAL

Twin-block appliance will be used for children who have Cl.II div.a malocclusion

Device: Myofunctional appliance

Interventions

Myifunctional appliance will be used for growing patients who have Cl.II div.1 malocclusion, two types of appliances are involved myobrace and twin=block appliance

Myobrace groupTwin-block group

Eligibility Criteria

Age8 Years - 14 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Growing children who need myofunctional appliance.
  • Cl II div. 1 malocclusion.
  • No previous orthodontic or orthopaedic treatments.

You may not qualify if:

  • Patients with systemic involvement.
  • Congenital malformations such as cleft lip and palate.
  • Facial deformities.
  • Finger sucking habit will be excluded

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

College of Dentistry-University of Baghdad

Baghdad, Al-Rusafa, 01110, Iraq

RECRUITING

College of Dentisry-University of Baghdad

Baghdad, Iraq

RECRUITING

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Blinding to treatment allocation is possible only for the outcomes assessor because the clinicians could know the intervention. All the trial documents will be labeled with the study ID number, which be used for participant identification and data collection without unmasking the allocation group.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 26, 2022

First Posted

May 12, 2022

Study Start

September 10, 2021

Primary Completion

July 10, 2024

Study Completion

August 10, 2024

Last Updated

November 28, 2023

Record last verified: 2023-11

Locations