The Contributions of the Multidisciplinary Management of Prosthesis Knee Infections in a Reference Center: A Retrospective Study About 52 Cases.Skin Coverage in a Reference Center: A Retrospective Study About 52 Cases

NCT05367726 | Unknown

• 1 other identifier: 776
• Study Type: observational
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

Acute and chronic infection of knee joint prosthesis can have several outcomes, the most feared of which is trans-femoral amputation. In order to save the limb while maintaining function, the management of these infections involves several specialists. Orthopedic surgeons are on the front line for carrying out bacteriological samples as well as for changing the material when necessary. The infectiologists coordinate this care by supervising each of the interventions by an antibiotic therapy adapted to the germs and by ensuring the occurrence of adverse events related to the treatment. Plastic surgeons intervene when the skin cover of the knee is deemed to be precarious or when there is an identified loss of substance that could affect the prognosis of the prosthesis. The main objective of our study is to evaluate the success rate of skin coverage and functional recovery for patients cured of their infection. The secondary objective is the identification of risk factors for skin coverage in this population.

Conditions

Knee Joint Prosthesis Infection; Flap Necrosis; Skin Graft Complications

Keywords

knee joint prosthesis; Flap; Skin Graft

Outcome Measures

Primary Outcomes (1)

• rate of patients with prosthesis knee infection requiring skin coverage

  proportion of patients with prosthesis knee infection requiring skin coverage amaong all prosthesis knee infection

  2011-2021

Secondary Outcomes (1)

• description of the population at risk of coverage after prosthesis knee infection

  2011-2021

Study Arms (1)

patients having had skin coverage of the knee

patients having had skin coverage of the knee after or at the same time than an orthopedic surgery to treat a knee prosthesis infection

Other: patients having had skin coverage of the knee

Interventions

patients having had skin coverage of the knee OTHER

the cutaneous cover is not always optimal to protect the prosthesis, an act of reconstructive plastic surgery is then necessary

patients having had skin coverage of the knee

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with a prosthesis knee infection infection whose management requires skin covering plastic surgery

You may qualify if:

• Patients with a prosthesis knee infection whose management requires skin covering plastic surgery
• Surgical procedures performed at the Croix Rousse Hospital

You may not qualify if:

• none

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Hospices Civils de Lyon

Lyon, 69004, France

Location

Related Links

• website of crioac lyon

Central Study Contacts

Tristan Ferry, Md,PhD

CONTACT

04 26 73 29 38; tristan.ferry@chu-lyon.fr

Eugenie Mabrut, CRA

CONTACT

04 26 73 29 38; eugenie.mabrut@chu-lyon.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 5, 2022
• First Posted: May 10, 2022
• Study Start: May 1, 2022
• Primary Completion: June 1, 2022
• Study Completion: September 1, 2022
• Last Updated: May 10, 2022

Record last verified: 2022-05

Locations

FR (1)