Use of Probiotic Yogurt in Obese Women

NCT05364814 | Completed

• 1 other identifier: YuksekIU02
• Study Type: observational
• Target: 21
• Locations: 1 country
• Sites: 2

Brief Summary

This study aimed to examine the effects of using probiotic yogurt on body components (body weight, height, etc.) and digestive system (distention, gas, etc.) in obesity (obese women), which is an important public health problem all over the world.

Conditions

Obesity; Dysbioses

Outcome Measures

Primary Outcomes (1)

• Determining Change in Obesity

  * Mean percent change in initial and final body weight (kilogram) * Mean percent change initial and final waist circumference (cm): * Mean percent change initial and final waist/height ratio: It will be calculated by dividing waist circumference by height. The cut-off point of ratio will be taken as 0.5. * Mean percent change initial and final waist/hip ratio:The cut-off point for the Waist/Hip ratio, which was determined by dividing the waist circumference by the hip circumference, was determined as ≥0.90 cm for men and ≥0.85 cm for women. * Mean percent change initial and final fat mass: It measurement of individuals will be measured with the Body Composition Analyzer (in % and kg units). It is based on the difference in electrical permeability of fat-free tissue mass and fat. * Biochemical parameters was determined in mg/dL following the protocols established for: high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides and fasting glucose.

  1 time per week/5 weeks

Secondary Outcomes (1)

• Changes on the Gastrointestinal System

  1 time per week/5 weeks

Study Arms (1)

Obese Group

A single sample group . Anthropometric measurements were taken at the beginning of all patients. Yogurt with probiotic added to medical nutrition therapy was applied for 2 weeks.Anthropometric measurements were taken at the beginning of all patients. Yogurt with probiotic added to medical nutrition therapy was applied for 2 weeks. At the end of each week, food consumption records and scales were applied. During the wash out period, all patients were asked to comply with their diet only. After the wash out period, a different diet was started and the same procedures were repeated.During the wash out period, all patients were asked to comply with their diet only. After the wash out period, a different diet (with the addition of probiotic yogurt) was changed and the same procedures were repeated.

Eligibility Criteria

• Age: 25 Years - 45 Years
• Gender Eligibility Details: The female gender was preferred in terms of ensuring homogeneity and sustainability of the diet.
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

She was diagnosed with obesity by a doctor at Malatya Turgut Özal University Training and Research Hospital and was consulted to the Diet Polyclinic for appropriate Medical Nutrition Therapy; patients aged 25-45, female, with a BMI of 27 -35 kg/m2, who read and signed the voluntary consent form.

You may qualify if:

• Female patients aged 25-45 years, with a BMI of 27-35 kg/m2 diagnosed as obese by the doctor
• Female patients without a chronic disease
• Female patients between the ages of 25-45 with regular menstrual cycles,
• Female patients between the ages of 25-45 who are not pregnant or lactating
• Female patients who do not use drugs, herbal products, etc. nutritional supplements.

You may not qualify if:

• Patients with BMI≥ 36 kg/m2
• Patients with diabetes, gastrointestinal diseases, CRF, etc.
• Women in pregnancy and lactation period,
• Male patients
• Weight loss medicine etc. patients with drug use
• Patients who use antibiotics
• Patients using probiotics, propolis, herbal products, etc.
• Patients with menstrual irregularity
• Female patients who have entered the menopause

Sponsors & Collaborators

• Yuksek Ihtisas University: lead
• Malatya Egitim Ve Arastirma Hastanesi: collaborator
• Turgut Ozal University: collaborator

Study Sites (2)

Malatya Training and Research Hospital

Malatya, 44330, Turkey (Türkiye)

Location

Malatya Training and Research Hospital

Malatya, Turkey (Türkiye)

Location

Related Publications (3)

• Cancello R, Turroni S, Rampelli S, Cattaldo S, Candela M, Cattani L, Mai S, Vietti R, Scacchi M, Brigidi P, Invitti C. Effect of Short-Term Dietary Intervention and Probiotic Mix Supplementation on the Gut Microbiota of Elderly Obese Women. Nutrients. 2019 Dec 10;11(12):3011. doi: 10.3390/nu11123011.

  PMID: 31835452 BACKGROUND

• Wang ZB, Xin SS, Ding LN, Ding WY, Hou YL, Liu CQ, Zhang XD. The Potential Role of Probiotics in Controlling Overweight/Obesity and Associated Metabolic Parameters in Adults: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2019 Apr 15;2019:3862971. doi: 10.1155/2019/3862971. eCollection 2019.

  PMID: 31118956 BACKGROUND

• Mazloom K, Siddiqi I, Covasa M. Probiotics: How Effective Are They in the Fight against Obesity? Nutrients. 2019 Jan 24;11(2):258. doi: 10.3390/nu11020258.

  PMID: 30678355 BACKGROUND

MeSH Terms

Conditions

Obesity; Dysbiosis

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Pathologic Processes

Study Officials

• Sevan ÇETİN ÖZBEK

  Yüksek Ihtisas University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Proffesor

Study Record Dates

• First Submitted: May 3, 2022
• First Posted: May 6, 2022
• Study Start: February 2, 2022
• Primary Completion: April 1, 2022
• Study Completion: April 15, 2022
• Last Updated: July 18, 2022

Record last verified: 2022-07

Locations

TU (2)