Tenodesis Grip Strength With Functional Hand Recovery in Cervical Spinal Cord Injury

NCT05356442 | Completed

• 1 other identifier: REC/Lhr/22/0209 Amna Ali
• Study Type: observational
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

Spinal cord injury (SCI) is devastating event, the individual become significant burden on their family and society SCI is impairments of sensory, motor and autonomic functions. There is no proper cure and care after SCI, no proper assessment and treatment is present in under developed countries Cross sectional study design will be used and 75 patients included in this study. The population included age 21-55 years, both gender included, teraplegic with lesion level C5-C7, Mini Mental State of Examination ≥24, patient should be medically stable. The patient excluded with history of peripheral nerve lesion as brachial pluxes impairment. For assessment of hand function tools should be used tenodesis grip strength is assessed Graded Redefined Assessment of Strength sensibility and prehension (GRASSP test), and functional hand recovery assessed by jebsen\_Taylor Hand function test (JTHFT\_IT), hand dynamo meter for grip strength, Action Arm reach test for hand function and spinal cord independence measure will be used. Pearson correlation will be uses to find the association between hand grip strength and functional activities of hand. The collected data will be analyzed by using SPSS 23.

Conditions

Spinal Cord Injuries

Keywords

spinal cord injury, pain ,tenodesis grip, strength

Outcome Measures

Primary Outcomes (4)

• Graded Redefined Assessment of Strength Sensibility and Prehension (GRASSP)

  GRASSP is a clinical research tool for sensory and motor impairment data of upper limb in cervical spinal cord injury. GRASSP have three components, first is sensibility domain test site is selected by dermatome, second is strength and tone domain in which muscle tested by myotomes and third is prehension domain in which segmental influence movement pattern

  8 months

• Jebsen-Taylor hand function test (JTHFT-IT)

  JTHFT-IT is used in people with tetraplegia. This scale is used for assessment of arm and hand , including basic functions as moving objects in which turning and pick up small objects , lifting small objects and light weighted objects also grasp and release including complex functions as dress up and toileting. The maximum time for execution of seven items will be 14min since the maximum execution time for each item is 120s

  8 months

• Hand Grip Dynamometer Strength Tool

  It is used in correct position of arm and hand can vary in different grip strength, both for right and left hand will be accessed and scoring start from dominant hand. Interpretation for male in Ib and in( kg), poor in 88-95(Ib) and 40-43kg, average strength 105-114 in (Ib) and 48-51 in( kg) while good strength in 123-141(Ib) and 56-64(kg). and in females values are different poor strength 44-48(ib) and 34-38(kg) , average strength value will be 57-65(ib) and in 26-29 in (kg), while good strength rating is 75-84(ib) and 34-38(kg).

  8 months

• Spinal Cord Independence Measure

  There are basically three subscales. First is self care and also for hand function assessment in which 0-4 items and score is 0-20, second is respiration and sphincter management 5-8 items and score is 0-40 while third is mobility with 9-18 items and score is 0-40. Total score is 100 while total items are 19 and assessment completed in 30-45minutes.

  8 months

Eligibility Criteria

• Age: 21 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

SCI

You may qualify if:

• Age group is from 21 to 55 years.
• Both male and female
• Tetraplegic with neurological lesion level C5-C7
• Mini Mental State Examination ≥24
• Grade C and D will include in this study according to ASIA impairment scale
• Upper limb muscles in grade 0, 1, +1 according to modified Ashworth scale

You may not qualify if:

• Contracture of upper extremity with C5-C7 cervical SCI.
• Combined peripheral or central nervous system disease
• History of peripheral nerve lesion as brachial plexus impairment
• Previously known poly Neuropathy or sever cranio cerebral injury
• History of Fracture or any surgical procedure in hand area.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Hospital

Lahore, Punjab Province, 54000, Pakistan

Location

Related Publications (4)

• O'Connor PJ. Prevalence of spinal cord injury in Australia. Spinal Cord. 2005 Jan;43(1):42-6. doi: 10.1038/sj.sc.3101666.

  PMID: 15326472 BACKGROUND

• Rahimi-Movaghar V, Saadat S, Rasouli MR, Ganji S, Ghahramani M, Zarei MR, Vaccaro AR. Prevalence of spinal cord injury in Tehran, Iran. J Spinal Cord Med. 2009;32(4):428-31. doi: 10.1080/10790268.2009.11754572.

  PMID: 19777865 BACKGROUND

• Jung HY, Lee J, Shin HI. The natural course of passive tenodesis grip in individuals with spinal cord injury with preserved wrist extension power but paralyzed fingers and thumbs. Spinal Cord. 2018 Sep;56(9):900-906. doi: 10.1038/s41393-018-0137-4. Epub 2018 May 22.

  PMID: 29789707 BACKGROUND

• Thorsen R, Binda L, Chiaramonte S, Dalla Costa D, Redaelli T, Occhi E, Beghi E, Ferrarin M. Correlation among lesion level, muscle strength and hand function in cervical spinal cord injury. Eur J Phys Rehabil Med. 2014 Feb;50(1):31-8. Epub 2013 Jul 2.

  PMID: 23820875 BACKGROUND

MeSH Terms

Conditions

Spinal Cord Injuries

Condition Hierarchy (Ancestors)

Spinal Cord Diseases; Central Nervous System Diseases; Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries

Study Officials

• Tehreem Mukhtar

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 28, 2022
• First Posted: May 2, 2022
• Study Start: April 25, 2022
• Primary Completion: December 25, 2022
• Study Completion: December 30, 2022
• Last Updated: April 3, 2023

Record last verified: 2023-03

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)